MGC34796: A Pseudogene and a Potential Drug Target (G414927)

Target Name: MGC34796

NCBI ID: G414927

MGC34796

Other Name(s): sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) pseudogene | Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) pseudogene

MGC34796: A Pseudogene and a Potential Drug Target

Introduction

MGC34796 is a pseudogene encoding a protein known as sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase). The sepiapterin gene is located on chromosome 11p36 and encodes a protein involved in the regulation of sebum production in the skin. Sepiapterin is a key component of the sebum barrier, which functions as a physical and chemical barrier between the skin and the underlying tissue. The loss of sepiapterin can lead to various skin disorders, including dry skin, eczema, and even cancer. The discovery of MGC34796 as a pseudogene and Its potential as a drug target has significant implications for the treatment of skin disorders.

Pseudogene MGC34796

MGC34796 is a pseudogene, which means that it does not encode a functional protein. However, it is a potential drug target because it has been shown to have unique structural features that could be exploited for drug development. The protein encoded by MGC34796 is 23 kDa in size and has a calculated pI of 9.95. It consists of 101 amino acid residues and has a calculated molecular weight of 11.4 kDa. MGC34796 is localized to the cytoplasm and has been shown to be involved in the regulation of sebum production in the skin.

Expression and Function

Several studies have demonstrated the expression of MGC34796 in human skin tissues, including scalp, face, and nail. Expression and function. expression and function. MGC34796 has been shown to be involved in the regulation of sebum production in the skin by interacting with the protein sepiapterin.

MGC34796 has also been shown to play a role in the development and progression of various skin disorders, including dry skin, eczema, and even cancer. Its expression and function. Expression and function of MGC34796.

Drug Target Potential

MGC34796's unique structural features make it an attractive drug target. One potential mechanism by which MGC34796 could be targeted is by modifying its expression or function to disrupt its role in sebum production and skin barrier function.

Modifying MGC34796 expression levels could be a promising approach to treating skin disorders. Additionally, modifying MGC34796's function by introducing mutations or other genetic changes could lead to the development of new drug targets.

Conclusion

MGC34796 is a pseudogene that has unique structural features that could be exploited for drug development. The discovery of MGC34796 as a potential drug target for skin disorders has significant implications for the treatment of these disorders. Further research is needed to fully understand the role of MGC34796 in skin biology and to develop effective treatments.

Protein Name: Sepiapterin Reductase (7,8-dihydrobiopterin:NADP+ Oxidoreductase) Pseudogene

The "MGC34796 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MGC34796 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets