Target Name: MPP1
NCBI ID: G4354
Review Report on MPP1 Target / Biomarker Content of Review Report on MPP1 Target / Biomarker
MPP1
Other Name(s): AAG12 | MAGUK p55 scaffold protein 1, transcript variant 4 | aging-associated gene 12 | MPP1 variant 3 | 55 kDa erythrocyte membrane protein (isoform 2) | erythrocyte membrane protein p55 | p55 | 55 kDa erythrocyte membrane protein (isoform 3) | EMP55 | PEMP | palmitoylated erythrocyte membrane protein | DXS552E | MAGUK p55 scaffold protein 1, transcript variant 3 | Membrane protein, palmitoylated 1 | membrane protein, palmitoylated 1, 55kDa | MRG1 | MPP1 variant 4 | EM55_HUMAN | Erythrocyte membrane protein p55 | MAGUK p55 scaffold protein 1, transcript variant 1 | membrane palmitoylated protein 1 | 55 kDa erythrocyte membrane protein (isoform 4) | Migration-related gene 1 | 55 kDa erythrocyte membrane protein | migration-related gene 1 | MPP1 variant 2 | 55 kDa erythrocyte membrane protein (isoform 1) | Membrane protein, palmitoylated 1, 55kDa | MAGUK p55 scaffold protein 1 | MAGUK p55 scaffold protein 1, transcript variant 2 | MPP1 variant 1 | Aging-associated gene 12

Understanding MPP1: Unlocking Its Potential as A Drug Target and Biomarker

MPP1 (Agglutinin-Induced Glycation and Proteasome-Mediated Degradation) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. It is a member of the superfamily of structurally similar proteins known as the glycophospholipids (GPLs) and is involved in a variety of cellular processes. One of the unique features of MPP1 is its ability to induce glycation, which is the covalent binding of sugar molecules to proteins. This process can lead to the formation of inclusion complexes, which can be harmful to the cell.

MPP1 has also been shown to play a role in the regulation of cellular processes that are important for brain function, such as the regulation of neurotransmitter release and the modulation of inflammation. In addition, MPP1 has been shown to be involved in the development and progression of a variety of diseases, including neurodegenerative disorders, cardiovascular disease, and cancer.

Given the potential role of MPP1 in cellular processes, it is an attractive target for drug development. Many studies have identified potential drug compounds that can inhibit the activity of MPP1, and further research is being conducted to determine the efficacy and safety of these compounds.

One of the challenges in studying MPP1 is the complexity of its cellular interactions. MPP1 is involved in a wide range of processes and has multiple functions, making it difficult to understand exactly how it functions in the cell. However, research into the mechanisms of MPP1 function is ongoing, and these efforts are likely to continue to provide new insights into the biology of this protein.

In addition to its potential as a drug target, MPP1 is also a potential biomarker for a variety of diseases. The ability of MPP1 to induce glycation and the formation of inclusion complexes makes it an attractive candidate for use as a diagnostic marker for a variety of diseases, including neurodegenerative disorders, cardiovascular disease, and cancer.

Overall, MPP1 is a protein that has significant potential as a drug target and biomarker. Further research is needed to fully understand its functions in the cell and its potential as a therapeutic agent.

Protein Name: MAGUK P55 Scaffold Protein 1

Functions: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity)

The "MPP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MPP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MPP2 | MPP3 | MPP4 | MPP7 | MPPE1 | MPPED1 | MPPED2 | MPPED2-AS1 | MPRIP | MPST | MPTX1 | MPV17 | MPV17L | MPV17L2 | MPZ | MPZL1 | MPZL2 | MPZL3 | MR1 | MRAP | MRAP2 | MRAS | MRC1 | MRC2 | MRE11 | MREG | MRFAP1 | MRFAP1L1 | MRGBP | MRGPRD | MRGPRE | MRGPRF | MRGPRF-AS1 | MRGPRG | MRGPRX1 | MRGPRX2 | MRGPRX3 | MRGPRX4 | MRI1 | MRLN | MRM1 | MRM2 | MRM3 | MRNIP | MRO | MROCKI | MROH1 | MROH2A | MROH2B | MROH3P | MROH5 | MROH6 | MROH7 | MROH7-TTC4 | MROH8 | MROH9 | MRPL1 | MRPL10 | MRPL11 | MRPL12 | MRPL13 | MRPL14 | MRPL15 | MRPL16 | MRPL17 | MRPL18 | MRPL19 | MRPL2 | MRPL20 | MRPL20-AS1 | MRPL20P1 | MRPL21 | MRPL22 | MRPL23 | MRPL23-AS1 | MRPL24 | MRPL27 | MRPL28 | MRPL3 | MRPL30 | MRPL33 | MRPL34 | MRPL35 | MRPL35P2 | MRPL37 | MRPL38 | MRPL39 | MRPL4 | MRPL40 | MRPL41 | MRPL42 | MRPL42P5 | MRPL43 | MRPL44 | MRPL45 | MRPL45P1 | MRPL45P2 | MRPL46 | MRPL47 | MRPL48