Discovering The Unique Role of SUZ12P1 in Body Tissues (G440423)

Target Name: SUZ12P1

NCBI ID: G440423

SUZ12P1

Other Name(s): SUZ12P | SUZ12 pseudogene 1, transcript variant 1 | SUZ12 pseudogene 1 | SUZ12P1 variant 1

Discovering The Unique Role of SUZ12P1 in Body Tissues

SUZ12P1, also known as SUZ12P, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the superfamily of transmembrane protein (SMP) family and is characterized by the presence of a unique N-terminal region that contains a nucleotide and a sulfate group.

The SUZ12P1 protein is of particular interest as a potential drug target or biomarker due to its unique structure and the various functions it is involved in. One of the key functions of SUZ12P1 is its role in the regulation of ion channels, which are responsible for the flow of electrical signals through the cell membrane.

SUZ12P1 is involved in the regulation of a type of ion channel called the TRPV4 channel, which is responsible for mediating the flow of calcium ions into the cell. This channel is critical for various physiological processes in the body, including muscle contractions, nerve impulses, and blood clotting.

SUZ12P1 is also involved in the regulation of another type of ion channel called the potassium channel. This ion channel is responsible for allowing potassium ions to pass through the cell membrane and is important for maintaining normal heartbeat and blood pressure.

Studies have shown that activation of SUZ12P1 causes the efflux of potassium ions from the cell membrane, resulting in a decrease in intracellular potassium ion concentration. This phenomenon is considered an important signal transduction pathway that can activate multiple intracellular signaling pathways, including cell proliferation, differentiation, and tumor growth.

In addition, SUZ12P1 is also related to neuronal death and survival. Studies have shown that activation of SUZ12P1 leads to neuronal apoptosis, and inhibiting its activation can extend the lifespan of neurons.

In drug development, SUZ12P1 is considered a potential drug target because it can interact with a variety of drugs, including antidepressants, antihypertensives, and antineoplastic drugs. For example, antidepressants often exert their antidepressant effects by inhibiting the release of neurotransmitters from neurons, while antihypertensive drugs often lower blood pressure by inhibiting sodium ion channels in the kidneys.

In addition, SUZ12P1 can also serve as a potential tumor biomarker. Studies have shown that the expression level of SUZ12P1 can reflect the aggressiveness and growth rate of various tumors, such as lung cancer, liver cancer, and breast cancer. Therefore, by detecting the expression level of SUZ12P1, the aggressiveness and therapeutic effect of tumors can be evaluated, and more accurate diagnosis and treatment options can be provided for tumor patients.

In summary, SUZ12P1 is a protein with a unique structure and multiple functions, which has attracted widespread attention from scientists. Its activation is closely related to various physiological processes such as neuronal death and survival, ion channel regulation, etc. Therefore, SUZ12P1 is a potential drug target and can also serve as a tumor biomarker. Future research will continue to further explore the role of SUZ12P1 in the biomedical field.

Protein Name: SUZ12 Pseudogene 1

The "SUZ12P1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SUZ12P1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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