SYT11: Potential Drug Target for Various Diseases (G23208)

Target Name: SYT11

NCBI ID: G23208

SYT11

SYT11: Potential Drug Target for Various Diseases

SYT11 (MGC10881) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the transforming growth factor beta (TGF-β) family, which is known for their role in cell growth, differentiation, and repair. SYT11 has been shown to play a role in the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. As a potential drug target, SYT11 is being targeted for development as a new treatment for these diseases.

One of the key functions of SYT11 is its role in the regulation of cell proliferation. In fact, SYT11 has been shown to play a negative role in cell proliferation, by inhibiting the activity of the oncogene transforming growth factor beta (TGF-β). TGF-β is a well-known protein that plays a critical role in the development and maintenance of tissues, including organs, tissues, and organs. It is produced by the liver, and is involved in the regulation of cell growth, differentiation, and repair.

SYT11 is known to interact with TGF-β, and it has been shown to inhibit the activity of TGF-β by binding to its receptor. This interaction between SYT11 and TGF-β is important for the regulation of cell proliferation, as TGF-β is a potent stimulator of cell proliferation. By inhibiting the activity of TGF-β, SYT11 may be able to prevent the formation of cancer cells, and may be a useful target for cancer therapy.

Another function of SYT11 is its role in the regulation of cell differentiation. SYT11 has been shown to play a role in the regulation of neural stem cell (NSC) proliferation and differentiation. NSC are a type of cell that have the ability to develop into any type of cell in the nervous system, and are important for the development and maintenance of neural tissues. By regulating the proliferation and differentiation of NSC, SYT11 may be able to contribute to the development of new treatments for neurodegenerative diseases.

In addition to its role in cell proliferation and differentiation, SYT11 is also involved in the regulation of inflammation. It has been shown to play a role in the regulation of immune cell function, and may be involved in the development of autoimmune disorders. For example, studies have shown that SYT11 is expressed in immune cells, and that it is involved in the regulation of the activation and function of these cells. This involvement in immune cell regulation may make SYT11 a useful target for the development of new treatments for autoimmune disorders.

Finally, SYT11 is also involved in the regulation of cell survival. It has been shown to play a role in the regulation of cell survival, by preventing the programmed cell death (apoptosis) that occurs when cells are no longer needed. This regulation of cell survival is important for the maintenance of tissues and organs, and may be involved in the development of a variety of diseases.

In conclusion, SYT11 is a protein that is involved in a variety of important functions in the body, including cell proliferation, differentiation, and regulation of inflammation and cell survival. As a potential drug target, SYT11 is being targeted for development as a new treatment for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of SYT11 in these diseases, and to develop safe and effective treatments.

Protein Name: Synaptotagmin 11

Functions: Synaptotagmin family member involved in vesicular and membrane trafficking which does not bind Ca(2+). Inhibits clathrin-mediated and bulk endocytosis, functions to ensure precision in vesicle retrieval. Plays an important role in dopamine transmission by regulating endocytosis and the vesicle-recycling process. Essential component of a neuronal vesicular trafficking pathway that differs from the synaptic vesicle trafficking pathway but is crucial for development and synaptic plasticity. In macrophages and microglia, inhibits the conventional cytokine secretion, of at least IL6 and TNF, and phagocytosis. In astrocytes, regulates lysosome exocytosis, mechanism required for the repair of injured astrocyte cell membrane (By similarity). Required for the ATP13A2-mediated regulation of the autophagy-lysosome pathway (PubMed:27278822)

The "SYT11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SYT11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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