Target Name: SYNM
NCBI ID: G23336
Review Report on SYNM Target / Biomarker Content of Review Report on SYNM Target / Biomarker
SYNM
Other Name(s): SYN | SYNEM_HUMAN | Synemin | Synemin alpha | synemin alpha | Synemin, transcript variant A | KIAA0353 | desmuslin | synemin, intermediate filament protein | synemin | Synemin (isoform A) | synemin beta | SYNM variant A | DMN | Desmuslin

SYNM: A Protein with Potential Drug Targets for Neurological Disorders

SYNM is a protein that is expressed in various tissues throughout the body, including the brain, spinal cord, and peripheral nerves. It is a key player in the development and maintenance of synaptic plasticity, which is the ability of the nervous system to change and adapt over time.

Recent studies have identified SYNM as a potential drug target for a variety of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression. This is because SYNM has been shown to play a role in the pathophysiology of these conditions, as well as in the development of other neurological disorders.

One of the key mechanisms by which SYNM contributes to the development and progression of these conditions is its role in the regulation of synaptic plasticity.Synaptic plasticity is the ability of the nervous system to change and adapt over time, and it is a critical factor in the development and maintenance of learning and memory.

SYNM is involved in the regulation of several key steps in synaptic plasticity, including the formation of new neurons, the modulation of neurotransmitter release, and the formation of synapses. Studies have shown that SYNM plays a critical role in the regulation of neurotransmitter release, by which it helps to maintain the levels of neurotransmitters in the brain and spinal cord that are necessary for proper functioning.

In addition to its role in synaptic plasticity, SYNM has also been shown to be involved in the regulation of other important processes in the nervous system. For example, studies have shown that SYNM plays a critical role in the regulation of ion traffic in the brain , which is important for the proper functioning of neurons and other cells.

Given the potential role of SYNM in the development and progression of a variety of neurological and psychiatric disorders, researchers are actively exploring potential drug targets for this protein. Various neurological and psychiatric diseases including Alzheimer's disease, Parkinson's disease and depression.

Protein Name: Synemin

Functions: Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteromeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteromeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells

The "SYNM Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SYNM comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SYNM-AS1 | SYNPO | SYNPO2 | SYNPO2L | SYNPO2L-AS1 | SYNPR | SYNPR-AS1 | SYNRG | Syntaxin | Synuclein | SYP | SYPL1 | SYPL2 | SYS1 | SYS1-DBNDD2 | SYT1 | SYT10 | SYT11 | SYT12 | SYT13 | SYT14 | SYT15 | SYT15B | SYT16 | SYT17 | SYT2 | SYT3 | SYT4 | SYT5 | SYT6 | SYT7 | SYT8 | SYT9 | SYTL1 | SYTL2 | SYTL3 | SYTL4 | SYTL5 | SYVN1 | SZRD1 | SZRD1P1 | SZT2 | T-Box transcription factor (TBX) | T-Type Calcium Channel | TAAR1 | TAAR2 | TAAR3P | TAAR5 | TAAR6 | TAAR8 | TAAR9 | TAB1 | TAB2 | TAB2-AS1 | TAB3 | TAC1 | TAC3 | TAC4 | TACC1 | TACC2 | TACC3 | Tachykinin Receptor | TACO1 | TACR1 | TACR2 | TACR3 | TACSTD2 | TADA1 | TADA2A | TADA2B | TADA3 | TAF1 | TAF10 | TAF11 | TAF11L2 | TAF11L3 | TAF12 | TAF12-DT | TAF13 | TAF15 | TAF1A | TAF1A-AS1 | TAF1B | TAF1C | TAF1D | TAF1L | TAF2 | TAF3 | TAF4 | TAF4B | TAF5 | TAF5L | TAF5LP1 | TAF6 | TAF6L | TAF7 | TAF7L | TAF8 | TAF9 | TAF9B