OR4F21: A Potential Drug Target and Biomarker (G441308)

OR4F21: A Potential Drug Target and Biomarker

Introduction

The olfactory system is a critical sense modality that enables individuals to identify and remember various scents. Olfactory receptor, family 4 (OR4F21), is a transmembrane protein that plays a crucial role in this process. OR4F21 is a pseudogene, which means that it encodes a protein but does not have the function of the OR4F21 gene. Despite its non-functional nature, OR4F21 has been shown to interact with various molecules, including G protein-coupled receptors (GPCRs), which are involved in sensory signaling. Therefore, OR4F21 is a potential drug target and biomarker.

Drug Target Potential

OR4F21 has been identified as a potential drug target due to its unique structure and its interaction with GPCRs. GPCRs are a family of transmembrane proteins that play a crucial role in sensory signaling. They are involved in the perception of various stimuli, including scents, sounds , and touch. GPCRs have multiple kinases that are involved in intracellular signaling. Therefore, targeting GPCRs is a promising strategy for developing new drugs that can treat various diseases.

OR4F21 has been shown to interact with multiple GPCRs, including GPCR7, GPCR8, and GPCR10. GPCR7 and GPCR8 are involved in the perception of sweet and sour scents, while GPCR10 is involved in the perception of bitter taste. These interactions suggest that OR4F21 may be a Useful drug target for treating disorders related to sensory perception.

Biomarker Potential

OR4F21 has also been shown to be involved in the production of various biomarkers for various diseases. For example, OR4F21 has been shown to be involved in the production of cortisol, which is a hormone that is released in response to stress. to be involved in the regulation of cortisol production, which may have implications for treating disorders related to stress, such as anxiety and depression.

OR4F21 has also been shown to be involved in the production of other biomarkers, including histamine H1 receptor (H1R), which is involved in immune responses and inflammation. Molecular interactions, thereby affecting signaling pathways in immune cells and nerve cells.

Conclusion

OR4F21 is a pseudogene that has been shown to interact with multiple GPCRs involved in sensory signaling. Therefore, it is a potential drug target and biomarker. Further research is needed to fully understand the role of OR4F21 in sensory signaling and to explore its potential as a drug target and biomarker.

Protein Name: Olfactory Receptor Family 4 Subfamily F Member 21

Functions: Odorant receptor

The "OR4F21 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR4F21 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

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