Target Name: ORC2
NCBI ID: G4999
Review Report on ORC2 Target / Biomarker Content of Review Report on ORC2 Target / Biomarker
ORC2
Other Name(s): origin recognition complex, subunit 2 homolog | Origin recognition complex protein 2 homolog | origin recognition complex protein 2 homolog | Origin recognition complex subunit 2, transcript variant 1 | ORC2_HUMAN | ORC2 variant 1 | ORC2L | origin recognition complex subunit 2 | Origin of replication 2-like | Origin recognition complex subunit 2

ORC2: Responsible for Recognizing The Origins of Linear DNA

ORC2 (Origin Recognition Complex, Subunit 2 Homolog) is a protein that plays a crucial role in the process of origin recognition in the universe. It is a subunit of the ORC2 complex, which is responsible for recognizing the origin of linear molecules in DNA. ORC2 is made up of multiple subunits that work together to recognize specific sequences in DNA.

One of the key functions of ORC2 is its ability to recognize the specific sequence of nucleotides that code for a protein. This is accomplished through the use of a unique combination of amino acids, which allows ORC2 to recognize specific sequences that are specific to each protein . ORC2 is able to achieve this high level of specificity through its unique structure and the way it functions.

ORC2 is also involved in the process of degradation, which is the breakdown of damaged or unnecessary DNA sequences. This is accomplished through the use of a unique mechanism that involves the formation of a protein-DNA complex, which is then degraded by a variety of enzymes. This ability to recognize and degrade damaged DNA is important for maintaining the integrity of DNA and the health of the cell.

In addition to its role in recognition and degradation, ORC2 is also involved in the process of DNA repair. This is accomplished through the use of a unique mechanism that involves the formation of a DNA-protein complex, which is then used to repair damaged DNA . ORC2 is able to achieve this high level of accuracy through its unique structure and the way it functions.

ORC2 is also a potential drug target and a biomarker. The high level of specificity of ORC2 makes it an attractive target for drug development, as it is able to recognize specific sequences with high accuracy. In addition, the process of origin recognition, degradation, and repair, which are all involved in the function of ORC2, make it an attractive target for biomarker development.

Overall, ORC2 is a protein that plays a crucial role in the process of origin recognition in the universe. Its unique structure and the way it functions make it an attractive target for drug development and biomarker development. Further research is needed to fully understand the role of ORC2 in the process of origin recognition and its potential as a drug and biomarker.

Protein Name: Origin Recognition Complex Subunit 2

Functions: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3

The "ORC2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ORC2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ORC3 | ORC4 | ORC5 | ORC6 | Orexin receptor | Organic anion transporters (OATs) | Organic cation transporter | Origin recognition complex | ORM1 | ORM2 | ORMDL1 | ORMDL2 | ORMDL3 | OS9 | OSBP | OSBP2 | OSBPL10 | OSBPL11 | OSBPL1A | OSBPL2 | OSBPL3 | OSBPL5 | OSBPL6 | OSBPL7 | OSBPL8 | OSBPL9 | OSCAR | OSCP1 | OSER1 | OSER1-DT | OSGEP | OSGEPL1 | OSGEPL1-AS1 | OSGIN1 | OSGIN2 | OSM | OSMR | OSMR-DT | OSR1 | OSR2 | OST4 | OSTC | OSTCP1 | OSTF1 | OSTF1P1 | OSTM1 | OSTM1-AS1 | OSTN | OSTN-AS1 | OTC | OTOA | OTOAP1 | OTOF | OTOG | OTOGL | OTOL1 | OTOP1 | OTOP2 | OTOP3 | OTOR | OTOS | OTP | OTUB1 | OTUB2 | OTUD1 | OTUD3 | OTUD4 | OTUD5 | OTUD6A | OTUD6B | OTUD6B-AS1 | OTUD7A | OTUD7B | OTULIN | OTULINL | OTX1 | OTX2 | OTX2-AS1 | OVAAL | OVCA2 | OVCH1 | OVCH1-AS1 | OVCH2 | OVGP1 | OVOL1 | OVOL1-AS1 | OVOL2 | OVOL3 | OVOS2 | OXA1L | OXA1L-DT | OXCT1 | OXCT1-AS1 | OXCT2 | OXCT2P1 | OXER1 | OXGR1 | OXLD1 | OXNAD1 | OXR1