CPLANE2: A Potential Drug Target and Biomarker for Cancer (G79363)

Target Name: CPLANE2

NCBI ID: G79363

CPLANE2

CPLANE2: A Potential Drug Target and Biomarker for Cancer

Cancer is a leading cause of morbidity and mortality worldwide, and its development and progression are tightly regulated by a complex interplay of genetic and epigenetic factors. The regulation of cell polarity is a critical aspect of cancer biology, as abnormal cell polarity can contribute to the development and progression of cancer. CPLANE2, a gene that encodes a protein involved in the regulation of cell polarity, has recently been identified as a potential drug target and biomarker for cancer.

CPLANE2: Structure and Function

CPLANE2 is a gene that encodes a protein with 156 amino acid residues. The protein has a unique structure, with a long N-terminus that contains a putative transmembrane domain and a C-terminus that contains a protein-coding domain. The putative transmembrane domain is composed of a variable region that includes an extracellular domain responsible for interactions with cell surface receptors and a cytoplasmic domain that is involved in protein-protein interactions. The C-terminus domain is composed of a variable region that includes a unique structural motif known as a \"尾-strand-rich region.\"

CPLANE2 is expressed in a wide range of tissues and cells, including human tissues, tissues from cancer cell lines, and cancer cells themselves. It has been shown to be involved in the regulation of cell polarity, as well as the development and progression of cancer.

CPLANE2 as a Drug Target

CPLANE2 has been identified as a potential drug target due to its involvement in the regulation of cell polarity and its association with the development of cancer. Several studies have shown that inhibition of CPLANE2 can lead to the disruption of cell polarity, leading to the formation of cancer cells.

One of the potential mechanisms by which CPLANE2 may contribute to cancer development is its role in the regulation of the Wnt signaling pathway. Wnt signaling is a critical factor in cancer development, as it regulates cell proliferation and survival. Several studies have shown that the Wnt signaling pathway is involved in the development of cancer, and that inhibition of its activity may be a useful strategy for cancer treatment.

CPLANE2 has been shown to be involved in the regulation of the Wnt signaling pathway in several ways. First, it has been shown to encode a protein that can interact with the Wnt receptor, a protein that plays a critical role in the regulation of cell polarity. Second, it has been shown to encode a protein that can inhibit the activity of the Wnt signaling pathway, a protein that is involved in cell proliferation and survival.

CPLANE2 as a Biomarker

CPLANE2 has also been shown to be a potential biomarker for cancer, as its expression has been shown to be altered in a variety of cancer types. For example, several studies have shown that CPLANE2 is downregulated in cancer cells, while it is upregulated in normal tissues. This suggests that CPLANE2 may be a useful biomarker for cancer diagnosis and monitoring.

In addition, several studies have shown that CPLANE2 can be used as a target for cancer immunotherapy. Cancer immunotherapy is a promising strategy for cancer treatment, as it uses the body's immune system to fight cancer cells. CPLANE2 has been shown to be involved in the regulation of immune cell function, as it has been shown to encode a protein that can interact with

Protein Name: Ciliogenesis And Planar Polarity Effector Complex Subunit 2

Functions: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity)

The "CPLANE2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CPLANE2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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