Target Name: LAP3
NCBI ID: G51056
Review Report on LAP3 Target / Biomarker Content of Review Report on LAP3 Target / Biomarker
LAP3
Other Name(s): LAPEP | peptidase S | Cysteinylglycine-S-conjugate dipeptidase | Prolyl aminopeptidase | Leucine aminopeptidase | proline aminopeptidase | Peptidase S | leucine aminopeptidase 3 | PEPS | prolyl aminopeptidase | AMPL_HUMAN | LAP | Proline aminopeptidase | Leucyl aminopeptidase 3 | cysteinylglycine-S-conjugate dipeptidase | Leucine aminopeptidase 3 | leucyl aminopeptidase | epididymis secretory protein Li 106 | Cytosol aminopeptidase | Leucyl aminopeptidase | LAP-3 | HEL-S-106

LAP3: A Protein Interaction Hub with Potential Therapeutic Applications

LAP3 (LAPEP) is a protein that is expressed in various tissues throughout the body, including the brain, pancreas, and heart. It is a member of the tensin receptor family, which includes proteins that are involved in various physiological processes, including stress response, inflammation, and metabolism.

One of the unique features of LAP3 is its ability to interact with other proteins that are involved in the same signaling pathways. This interaction between LAP3 and its downstream targets is known as \"conservative\" and allows LAP3 to play a critical role in various biological processes.

In addition to its role in signaling pathways, LAP3 has also been shown to have a direct impact on cellular processes that are important for tissue repair and regeneration. This is because LAP3 is involved in the production of various signaling molecules, including growth factors and cytokines , which are important for the recruitment of immune cells and the initiation of cell proliferation and differentiation.

LAP3 is also involved in the regulation of cellular stress responses, which are critical for maintaining cellular homeostasis in response to environmental stimuli, such as stress, radiation, and Chemical-Induced-Cell-Stress (CIS).

The potential therapeutic benefits of LAP3 are significant, as it is an attractive target for drug development due to its unique structure and the diverse range of downstream targets that it interacts with. LAP3 has been shown to play a critical role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

In addition to its potential therapeutic applications, LAP3 is also a valuable research tool for the study of signaling pathways and cellular processes. The structure and function of LAP3 have been extensively studied, and these studies have shed light on the complex interplay between different signaling pathways and their role in the development and maintenance of cellular homeostasis.

Overall, LAP3 is a protein that continues to be an important focus of research in the fields of biology and medicine. Its unique structure and the diverse range of downstream targets make it an attractive target for drug development, and its role in the regulation of cellular stress responses and its involvement in the development of various diseases make it a valuable tool for the study of signaling pathways and cellular processes.

Protein Name: Leucine Aminopeptidase 3

Functions: Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status

The "LAP3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LAP3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

LAP3P2 | LAPTM4A | LAPTM4B | LAPTM4BP2 | LAPTM5 | Large Conductance BK(Ca) Potassium Channel (Maxi K+ Channel) | LARGE-AS1 | LARGE1 | LARGE2 | LARP1 | LARP1B | LARP4 | LARP4B | LARP4P | LARP6 | LARP7 | LARS1 | LARS2 | LAS1L | LASP1 | LAT | LAT2 | LATS1 | LATS2 | LAX1 | LAYN | LBH | LBHD1 | LBP | LBR | LBX1 | LBX1-AS1 | LBX2 | LBX2-AS1 | LCA5 | LCA5L | LCAL1 | LCAT | LCDR | LCE1A | LCE1B | LCE1C | LCE1D | LCE1E | LCE1F | LCE2A | LCE2B | LCE2C | LCE2D | LCE3A | LCE3B | LCE3C | LCE3D | LCE3E | LCE4A | LCE5A | LCE6A | LCIIAR | LCK | LCLAT1 | LCMT1 | LCMT2 | LCN1 | LCN10 | LCN12 | LCN15 | LCN1P1 | LCN1P2 | LCN2 | LCN6 | LCN8 | LCN9 | LCNL1 | LCOR | LCORL | LCP1 | LCP2 | LCT | LCT-AS1 | LCTL | LDAF1 | LDAH | LDB1 | LDB2 | LDB3 | LDC1P | LDHA | LDHAL6A | LDHAL6B | LDHAL6CP | LDHAP5 | LDHB | LDHBP1 | LDHC | LDHD | LDLR | LDLRAD1 | LDLRAD2 | LDLRAD3 | LDLRAD4