Target Name: SIAE
NCBI ID: G54414
Review Report on SIAE Target / Biomarker Content of Review Report on SIAE Target / Biomarker
SIAE
Other Name(s): Sialic acid-specific acetylesterase II | sialic acid-specific acetylesterase II | LSE | sialic acid acetylesterase | MGC87009 | Cytosolic sialic acid 9-O-acetylesterase homolog | YSG2 | CSEC | Sialate O-acetylesterase | SIAE_HUMAN | SIAE variant 1 | AIS6 | Sialic acid-specific 9-O-acetylesterase | cytosolic sialic acid 9-O-acetylesterase homolog | H-Lse | CSE-C | Sialic acid acetylesterase, transcript variant 1 | Sialate O-acetylesterase (isoform 1)

SIAE: A Drug Target / Disease Biomarker

SIAE, or Sodium-Glucose Isotope Exchange, is a protein that is expressed in various tissues throughout the body. It is involved in the regulation of sodium and glucose levels in the body, and is a potential drug target or biomarker for several diseases.

SIAE is a key protein that is expressed in the endoplasmic reticulum, which is the cell organ that synthesizes and modifies proteins. It is composed of two distinct chains that are held together by a disulfide bond. The two chains have different lengths and functions, with one chain having 156 amino acids and the other having 168 amino acids.

SIAE is involved in the regulation of sodium and glucose levels in the body. It helps to maintain the proper balance of these two ions in the body, which is essential for many physiological processes, including muscle and nerve function, nerve signaling, and the regulation of blood pressure.

SIAE is also involved in the regulation of water and electrolyte balance. It helps to regulate the levels of water and electrolytes in the body, which is important for maintaining the proper balance of these substances and for maintaining the health of the body's cells and tissues.

SIAE is a potential drug target or biomarker for several diseases, including hypertension, diabetes, and heart disease. High blood pressure, or hypertension, is a common condition that can lead to a range of health problems, including heart disease, stroke, and kidney damage. Diabetes is a disease that is characterized by high blood sugar levels, and it can also lead to a range of health problems, including heart disease, stroke, and kidney damage. Heart disease is a condition that can lead to chest pain, shortness of breath, and heart failure, and it is a leading cause of death in the United States.

SIAE may be a drug target for hypertension because it is involved in the regulation of sodium and glucose levels in the body. High blood pressure is often associated with an imbalance of sodium and glucose, and SIAE may help to regulate these levels to help maintain the proper balance.

SIAE may also be a drug target for diabetes because it is involved in the regulation of sodium and glucose levels in the body. Diabetes is a disease that is characterized by high blood sugar levels, and SIAE may help to regulate these levels to help maintain the proper balance.

SIAE may also be a biomarker for heart disease because it is involved in the regulation of sodium and glucose levels in the body. High blood pressure, or hypertension, is a common condition that can lead to heart disease, and SIAE may be involved in the regulation of these levels to help maintain the proper balance.

In conclusion, SIAE is a protein that is involved in the regulation of sodium and glucose levels in the body. It may be a potential drug target or biomarker for hypertension, diabetes, and heart disease due to its involvement in these processes. Further research is needed to fully understand the role of SIAE in these diseases and to develop effective treatments.

Protein Name: Sialic Acid Acetylesterase

Functions: Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid

The "SIAE Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SIAE comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SIAH1 | SIAH2 | SIAH3 | Sialidase | Sialyltransferase | SIDT1 | SIDT2 | SIGIRR | SIGLEC1 | SIGLEC10 | SIGLEC11 | SIGLEC12 | SIGLEC14 | SIGLEC15 | SIGLEC16 | SIGLEC17P | SIGLEC5 | SIGLEC6 | SIGLEC7 | SIGLEC8 | SIGLEC9 | SIGLECL1 | sigma Receptor | SIGMAR1 | Signal peptidase complex | Signal recognition particle | Signal recognition particle receptor | Signal Transducers and Activators of Transcription (STAT) | SIK1 | SIK2 | SIK3 | SIKE1 | SIL1 | SILC1 | SIM1 | SIM2 | SIMC1 | SIN3 complex | SIN3A | SIN3B | SINHCAF | SIPA1 | SIPA1L1 | SIPA1L1-AS1 | SIPA1L2 | SIPA1L3 | SIRPA | SIRPAP1 | SIRPB1 | SIRPB2 | SIRPB3P | SIRPD | SIRPG | SIRPG-AS1 | SIRT1 | SIRT2 | SIRT3 | SIRT4 | SIRT5 | SIRT6 | SIRT7 | SIT1 | SIVA1 | SIX1 | SIX2 | SIX3 | SIX3-AS1 | SIX4 | SIX5 | SIX6 | SKA1 | SKA1 complex | SKA2 | SKA2P1 | SKA3 | SKAP1 | SKAP1-AS2 | SKAP2 | Skeletal muscle troponin | SKI | SKIC2 | SKIC3 | SKIC8 | SKIDA1 | SKIL | SKINT1L | SKOR1 | SKOR2 | SKP1 | SKP1P2 | SKP2 | SLA | SLA2 | SLAIN1 | SLAIN2 | SLAM Family Member | SLAMF1 | SLAMF6 | SLAMF6P1 | SLAMF7