Target Name: SIGLEC15
NCBI ID: G284266
Review Report on SIGLEC15 Target / Biomarker Content of Review Report on SIGLEC15 Target / Biomarker
SIGLEC15
Other Name(s): Sig15 | Siglec-15 | CD33 antigen-like 3 | sialic acid binding Ig like lectin 15 | SIG15_HUMAN | SIGLEC-15 | CD33L3 | Sialic acid-binding Ig-like lectin 15 | HsT1361 | Sialic acid binding Ig like lectin 15 | CD33 molecule-like 3

SIGLEC15: A Potential Drug Target and Biomarker

Siglec15, also known as GLT-151, is a potential drug target and biomarker that has been identified by researchers using a combination of computational tools and experiments. The protein SIGLEC15 is expressed in various tissues and cells throughout the body, including the brain, and is involved in several cellular processes that are important for brain function.

One of the key functions of SIGLEC15 is its role in the regulation of cell adhesion. This protein helps to keep cells together in tight clusters, which are essential for the development and maintenance of tissues and organs. SIGLEC15 is also involved in the regulation of the migration of cells, which is critical for the formation of tissues and organs during development.

In addition to its role in cell adhesion and migration, SIGLEC15 is also involved in the regulation of the formation of new blood vessels. This protein helps to promote the formation of new blood vessels in the brain, which is critical for the delivery of oxygen and nutrients to the brain during times of injury or disease.

SIGLEC15 is also involved in the regulation of the production of neurotransmitters, which are important for the communication between cells and the brain. This protein helps to regulate the production of neurotransmitters, including dopamine, serotonin, and GABA, which are critical for the functioning of the brain.

One of the challenges in studying SIGLEC15 is its complex structure. This protein is composed of several domains, including an extracellular domain, a transmembrane domain, and an intracellular domain. The transmembrane domain of SIGLEC15 is thought to play a key role in its function, as it is involved in the regulation of cell adhesion and the formation of new blood vessels.

To better understand the function of SIGLEC15, researchers have used a variety of techniques to study its behavior. These techniques include biochemical assays, cell culture experiments, and imaging techniques, such as mass spectrometry. Using these techniques, researchers have been able to determine the mechanisms by which SIGLEC15 promotes cell adhesion, migration, and the formation of new blood vessels.

One potential approach to studying SIGLEC15 is to use small molecules to inhibit its function. This would allow researchers to determine the specific mechanisms by which SIGLEC15 promotes its functions and to identify potential drug targets. Additionally, researchers could use SIGLEC15 as a biomarker to diagnose and monitor certain diseases, such as cancer, neurodegenerative diseases, and cardiovascular diseases.

In conclusion, SIGLEC15 is a protein that is involved in several critical cellular processes that are important for brain function. Its complex structure and complex functions make it an attractive target for future research, and the use of small molecules to inhibit its function could provide valuable insights into its mechanisms of action. As research continues, it is likely that the role of SIGLEC15 in the regulation of cell behavior and the formation of tissues and organs will become increasingly important for our understanding of brain function and the development of new treatments for a variety of diseases.

Protein Name: Sialic Acid Binding Ig Like Lectin 15

Functions: Binds sialylated glycoproteins

The "SIGLEC15 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SIGLEC15 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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SIGLEC16 | SIGLEC17P | SIGLEC5 | SIGLEC6 | SIGLEC7 | SIGLEC8 | SIGLEC9 | SIGLECL1 | sigma Receptor | SIGMAR1 | Signal peptidase complex | Signal recognition particle | Signal recognition particle receptor | Signal Transducers and Activators of Transcription (STAT) | SIK1 | SIK2 | SIK3 | SIKE1 | SIL1 | SILC1 | SIM1 | SIM2 | SIMC1 | SIN3 complex | SIN3A | SIN3B | SINHCAF | SIPA1 | SIPA1L1 | SIPA1L1-AS1 | SIPA1L2 | SIPA1L3 | SIRPA | SIRPAP1 | SIRPB1 | SIRPB2 | SIRPB3P | SIRPD | SIRPG | SIRPG-AS1 | SIRT1 | SIRT2 | SIRT3 | SIRT4 | SIRT5 | SIRT6 | SIRT7 | SIT1 | SIVA1 | SIX1 | SIX2 | SIX3 | SIX3-AS1 | SIX4 | SIX5 | SIX6 | SKA1 | SKA1 complex | SKA2 | SKA2P1 | SKA3 | SKAP1 | SKAP1-AS2 | SKAP2 | Skeletal muscle troponin | SKI | SKIC2 | SKIC3 | SKIC8 | SKIDA1 | SKIL | SKINT1L | SKOR1 | SKOR2 | SKP1 | SKP1P2 | SKP2 | SLA | SLA2 | SLAIN1 | SLAIN2 | SLAM Family Member | SLAMF1 | SLAMF6 | SLAMF6P1 | SLAMF7 | SLAMF8 | SLAMF9 | SLBP | SLC corepressor complex | SLC10A1 | SLC10A2 | SLC10A3 | SLC10A4 | SLC10A5 | SLC10A6 | SLC10A7 | SLC11A1 | SLC11A2 | SLC12A1