SKIL: A Key Regulator of Cell Division and Tissue Organization

Target Name: SKIL

NCBI ID: G6498

SKIL

SKIL: A Key Regulator of Cell Division and Tissue Organization

SKIL (SKI-like protein-coding gene, transcript variant 1) is a gene that encodes a protein known as SKIL. SKIL is a scaffold protein that plays a crucial role in the regulation of cell division and the organization of tissues during development. It is a key regulator of the cell cycle, and its absence has been linked to various diseases, including cancer.

SKIL is a member of the SKI family of proteins, which are known for their ability to interact with and regulate the activity of microtubules, the protein structures that organize the cells of eukaryotic cells. The SKI family of proteins are also known as the spindle protein family, and they are involved in the proper functioning of the cell division process.

SKIL is a 168-amino acid protein that is expressed in a variety of tissues throughout the body, including the brain, pancreas, and gastrointestinal tract. It is primarily localized to the endoplasmic reticulum, where it can interact with and modulate the activity of microtubules.

SKIL has been shown to play a role in the regulation of cell division and the organization of tissues during development. It is a key regulator of the cell cycle, and its absence has been linked to various diseases, including cancer. For example, studies have shown that SKIL is often missing in human cancer cells, and that its overexpression has been associated with the development of various cancers, including breast, ovarian, and colorectal cancers.

In addition to its role in cell division, SKIL is also involved in the regulation of cell adhesion and migration. It has been shown to play a role in the formation of tight junctions, which are the molecular structures that mediate cell-cell communication and help to maintain tissue structure and function. SKIL has also been shown to be involved in the regulation of cell migration, and its absence has been linked to the development of various diseases, including cancer.

SKIL is also involved in the regulation of cell survival and stress response. It has been shown to play a role in the regulation of apoptosis, which is the process by which cells undergo programmed cell death in response to environmental stressors, such as UV radiation or toxic chemicals. SKIL has also been shown to play a role in the regulation of cell stress response, and its absence has been linked to the development of various diseases, including cancer.

In addition to its role in cell division, SKIL is also involved in the regulation of cell signaling and metabolism. It has been shown to play a role in the regulation of cell signaling pathways, including the regulation of the production of reactive oxygen species (ROS ), which are highly reactive molecules that can cause damage to cells if not properly regulated. SKIL has also been shown to play a role in the regulation of cell metabolism, including the regulation of protein synthesis and the detoxification of harmful substances.

SKIL is a potential drug target and a biomarker for various diseases, including cancer. Its absence or its hyperexpression have been linked to the development of various diseases, including cancer. For example, studies have shown that SKIL is often missing in human cancer cells, and that its overexpression has been associated with the development of various cancers, including breast, ovarian, and colorectal cancers. In addition, SKIL has also been shown to play a role in the regulation of cell adhesion and migration, and its absence has been linked to the development of various diseases, including cancer.

In conclusion, SKIL is a gene that encodes a protein that plays a crucial role in the regulation of cell division and the organization of tissues during development. It is a key regulator of the cell cycle, and its absence or its hyperexpression have been linked to various diseases, including cancer. Its potential as a drug target and biomarker makes it an attractive target for future research.

Protein Name: SKI Like Proto-oncogene

Functions: May have regulatory role in cell division or differentiation in response to extracellular signals

The "SKIL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SKIL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets