Target Name: SIL1
NCBI ID: G64374
Review Report on SIL1 Target / Biomarker Content of Review Report on SIL1 Target / Biomarker
SIL1
Other Name(s): SIL1 homolog, endoplasmic reticulum chaperone | ULG5 | SIL1 nucleotide exchange factor, transcript variant 2 | Nucleotide exchange factor SIL1 | SIL1_HUMAN | SIL1 variant 2 | MSS | BiP-associated protein | SIL1-like protein endoplasmic reticulum chaperone | ULG | SIL1 nucleotide exchange factor, transcript variant 1 | BAP | SIL1 nucleotide exchange factor | SIL1 variant 1

SIL1: A Protein Involved in Multiple Diseases

SIL1, or sil1 homolog, is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the superfamily of chaperone proteins, which are involved in the proper folding and transport of proteins from the cytoplasm to the endoplasmic reticulum (ER). SIL1 is unique among these chaperone proteins because it is able to interact with multiple different types of proteins, including drug targets.

SIL1 has been shown to interact with a wide range of drug targets, including proteins involved in cell signaling, neurodegenerative diseases, and personal health. Its interactions with these targets have the potential to modulate their activity, leading to therapeutic benefits. As a drug target, SIL1 is a promising biomarker for the development of new treatments for a variety of diseases.

One of the key challenges in studying SIL1 is its high level of expression in many different tissues, which can make it difficult to study its effects in specific contexts. However, researchers have been able to use techniques such as RNA interference and live cell imaging to manipulate SIL1 expression and study its effects.

SIL1 has also been shown to play a role in several neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. In these conditions, SIL1 is expressed at higher levels in the brains of affected individuals and has been implicated in the development and progression of these diseases. Studies have also shown that SIL1 interacts with proteins involved in the production and degradation of neurodegenerate proteins, which may contribute to its role in these conditions.

In addition to its potential role in neurodegenerative diseases, SIL1 has also been shown to be involved in a number of other processes in the body. For example, it has been shown to interact with proteins involved in cell signaling, including the protein T-cell receptor (TCR). This suggests that SIL1 may be involved in regulating the activity of TCR, which is a critical protein involved in the immune response.

SIL1 has also been shown to interact with proteins involved in cell adhesion and migration. These proteins help cells stick to each other and move through the body, and are involved in many important processes, including the development and maintenance of tissues and organs. SIL1 has has been shown to be involved in these processes, which may be important for its role in diseases such as cancer.

In addition to its role in these processes, SIL1 has also been shown to interact with proteins involved in the regulation of gene expression. These proteins help cells to turn on or off the genes that are expressed in their cells, and are involved in many important processes, including growth, development, and repair. SIL1 has been shown to be involved in these processes, which may be important for its role in diseases such as genetic disorders.

Overall, SIL1 is a protein that has the potential to be a drug target or biomarker in a variety of diseases. Its interactions with multiple different types of proteins make it an attractive target for researchers, and its role in several important processes in the body makes it a valuable tool for understanding the mechanisms of these diseases. Further research is needed to fully understand the effects of SIL1 and its potential as a drug or biomarker.

Protein Name: SIL1 Nucleotide Exchange Factor

Functions: Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5

The "SIL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SIL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SILC1 | SIM1 | SIM2 | SIMC1 | SIN3 complex | SIN3A | SIN3B | SINHCAF | SIPA1 | SIPA1L1 | SIPA1L1-AS1 | SIPA1L2 | SIPA1L3 | SIRPA | SIRPAP1 | SIRPB1 | SIRPB2 | SIRPB3P | SIRPD | SIRPG | SIRPG-AS1 | SIRT1 | SIRT2 | SIRT3 | SIRT4 | SIRT5 | SIRT6 | SIRT7 | SIT1 | SIVA1 | SIX1 | SIX2 | SIX3 | SIX3-AS1 | SIX4 | SIX5 | SIX6 | SKA1 | SKA1 complex | SKA2 | SKA2P1 | SKA3 | SKAP1 | SKAP1-AS2 | SKAP2 | Skeletal muscle troponin | SKI | SKIC2 | SKIC3 | SKIC8 | SKIDA1 | SKIL | SKINT1L | SKOR1 | SKOR2 | SKP1 | SKP1P2 | SKP2 | SLA | SLA2 | SLAIN1 | SLAIN2 | SLAM Family Member | SLAMF1 | SLAMF6 | SLAMF6P1 | SLAMF7 | SLAMF8 | SLAMF9 | SLBP | SLC corepressor complex | SLC10A1 | SLC10A2 | SLC10A3 | SLC10A4 | SLC10A5 | SLC10A6 | SLC10A7 | SLC11A1 | SLC11A2 | SLC12A1 | SLC12A2 | SLC12A2-DT | SLC12A3 | SLC12A4 | SLC12A5 | SLC12A5-AS1 | SLC12A6 | SLC12A7 | SLC12A8 | SLC12A9 | SLC13A1 | SLC13A2 | SLC13A3 | SLC13A4 | SLC13A5 | SLC14A1 | SLC14A2 | SLC15A1 | SLC15A2