SLAMF7: A Protein Involved in Cell Signaling, Inflammation and Metabolism

Target Name: SLAMF7

NCBI ID: G57823

SLAMF7

SLAMF7: A Protein Involved in Cell Signaling, Inflammation and Metabolism

SLAMF7 (19A) is a protein that is expressed in various tissues throughout the body, including the brain, muscle, and heart. It is a member of the Smin family, which is known for their role in cell signaling and intracellular structure. While the exact function of SLAMF7 is not yet well understood, research has shown that it plays a role in several important processes in the body, including cell signaling, inflammation, and metabolism.

One of the key functions of SLAMF7 is its role in cell signaling. The Smin family is known for their ability to regulate cell signaling pathways, and SLAMF7 is no exception. It has been shown to play a role in the regulation of several signaling pathways, including the TGF-β pathway and the Wnt pathway.

In addition to its role in cell signaling, SLAMF7 is also involved in the regulation of inflammation. The immune system is a critical component of the body's defense against infection and inflammation, and SLAMF7 is involved in the regulation of immune cell function.

SLAMF7 is also involved in the regulation of metabolism. It has been shown to play a role in the regulation of cellular metabolism, including the process of cell growth and division.

While the exact function of SLAMF7 is not yet well understood, research has shown that it is a potential drug target. Several studies have shown that inhibiting the activity of SLAMF7 has potential therapeutic benefits, including the treatment of various diseases, such as cancer, neurodegenerative diseases, and metabolic disorders.

In addition to its potential therapeutic applications, SLAMF7 is also an attractive biomarker for several diseases. The Smin family is known for their ability to serve as biomarkers for a wide range of diseases, including cancer, neurodegenerative diseases, and metabolism disorders. The ability of SLAMF7 to regulate cell signaling pathways makes it an attractive candidate for use as a biomarker for these diseases.

Overall, SLAMF7 is a protein that is involved in several important processes in the body. While its exact function is not yet well understood, research has shown that it has the potential to be a drug target and a biomarker for several diseases. Further research is needed to fully understand its role in the body and its potential applications in medicine.

Protein Name: SLAM Family Member 7

Functions: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (PubMed:11698418). Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K (PubMed:16339536). In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells (By similarity). May play a role in lymphocyte adhesion (PubMed:11802771). In LPS-activated monocytes negatively regulates production of pro-inflammatory cytokines (PubMed:23695528)

The "SLAMF7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLAMF7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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