Target Name: PON1
NCBI ID: G5444
Review Report on PON1 Target / Biomarker Content of Review Report on PON1 Target / Biomarker
PON1
Other Name(s): Paraoxonase | paraoxonase 1 | A-esterase 1 | serum aryldiakylphosphatase | Paraoxonase 1 | esterase A | Serum aryldialkylphosphatase 1 | arylesterase B-type | arylesterase 1 | paraoxonase B-type | ESA | Serum paraoxonase/arylesterase 1 | PON 1 | K-45 | Aromatic esterase 1 | Paraoxonase B-type | serum aryldialkylphosphatase 1 | MVCD5 | Esterase A | PON | Arylesterase B-type | Serum aryldiakylphosphatase | aromatic esterase 1 | PON1_HUMAN

PON1: A Drug Target / Disease Biomarker

PON1, also known as protamine phosphate nucleotide, is a drug target and biomarker that is of interest to researchers in the field of neurodegenerative diseases. PON1 is a protein that is expressed in the brain and is involved in the regulation of various cellular processes that are important for brain function.

One of the key functions of PON1 is its role in the regulation of neurotransmitter release from neurons. This is important for maintaining the proper functioning of the brain and for the proper treatment of neurodegenerative diseases.

Another function of PON1 is its role in the regulation of protein synthesis and degradation. This is important for maintaining the proper functioning of the brain and for the proper treatment of neurodegenerative diseases.

In addition to its role in neurotransmitter regulation and protein synthesis and degradation, PON1 is also involved in the regulation of cellular signaling pathways. This is important for maintaining the proper functioning of the brain and for the proper treatment of neurodegenerative diseases.

PON1 is also of interest as a potential drug target because of its role in the regulation of various cellular processes that are important for brain function. This makes it an attractive target for researchers to study and develop new treatments for neurodegenerative diseases.

In conclusion, PON1 is a protein that is expressed in the brain and is involved in the regulation of various cellular processes that are important for brain function. It is of interest as a potential drug target for the treatment of neurodegenerative diseases due to its role in the regulation of neurotransmitter release, protein synthesis and degradation, and cellular signaling pathways. Further research is needed to fully understand the role of PON1 in brain function and to develop new treatments for neurodegenerative diseases.

Protein Name: Paraoxonase 1

Functions: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation

The "PON1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PON1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PON2 | PON3 | POP1 | POP4 | POP5 | POP7 | POPDC2 | POPDC3 | POR | PORCN | POSTN | POT1 | POT1-AS1 | Potassium Channels | POTEA | POTEB | POTEB2 | POTEB3 | POTEC | POTED | POTEE | POTEF | POTEG | POTEH | POTEI | POTEJ | POTEKP | POTEM | POU-Domain transcription factors | POU1F1 | POU2AF1 | POU2AF2 | POU2AF3 | POU2F1 | POU2F2 | POU2F3 | POU3F1 | POU3F2 | POU3F3 | POU3F4 | POU4F1 | POU4F2 | POU4F3 | POU5F1 | POU5F1B | POU5F1P3 | POU5F1P4 | POU5F1P5 | POU5F2 | POU6F1 | POU6F2 | PP12613 | PP2D1 | PP7080 | PPA1 | PPA2 | PPAN | PPAN-P2RY11 | PPARA | PPARD | PPARG | PPARGC1A | PPARGC1B | PPAT | PPATP1 | PPBP | PPBPP2 | PPCDC | PPCS | PPDPF | PPDPFL | PPEF1 | PPEF2 | PPFIA1 | PPFIA2 | PPFIA3 | PPFIA4 | PPFIBP1 | PPFIBP2 | PPHLN1 | PPIA | PPIAL4A | PPIAL4D | PPIAL4E | PPIAL4F | PPIAL4G | PPIAL4H | PPIAP19 | PPIAP21 | PPIAP22 | PPIAP29 | PPIAP30 | PPIAP35 | PPIAP43 | PPIAP45 | PPIAP46 | PPIAP51 | PPIAP54 | PPIAP59 | PPIAP66