PPIAL4E: A Potential Drug Target and Biomarker for Various Diseases

Target Name: PPIAL4E

NCBI ID: G730262

PPIAL4E

PPIAL4E: A Potential Drug Target and Biomarker for Various Diseases

PPIAL4E (PAL4F-HUMAN) is a protein that is expressed in human tissues and has been shown to play a role in various physiological processes in the body. One of the most promising aspects of PPIAL4E is its potential as a drug target or biomarker. This This article will explore the biology of PPIAL4E, its potential drug targets, and its role as a biomarker in various diseases.

Biology of PPIAL4E

PPIAL4E is a member of the PPIAL family, which includes several related proteins that are involved in the regulation of ion channels and intracellular signaling pathways. These proteins are characterized by the presence of a specific domain called the PPIAL motif, which is a conserved sequence that is involved in the regulation of ion channels and intracellular signaling pathways.

PPIAL4E is a 21-kDa protein that is expressed in various human tissues, including brain, heart, and muscle. It is involved in the regulation of ion channels, including the potassium channel K+ channels. K+ channels are responsible for the rapid diffusion of sodium and potassium ions into and out of cells, and they play a crucial role in various physiological processes, including muscle contractions and heart rate.

In addition to its role in ion channel regulation, PPIAL4E is also involved in the regulation of intracellular signaling pathways. It has been shown to play a role in several signaling pathways, including the TGF-β pathway and the PI3K/Akt pathway. These pathways are involved in the regulation of cell growth, differentiation, and survival, and are important for the development and progression of many diseases.

Potential Drug Targets

The potential drug targets for PPIAL4E are numerous. One of the most promising targets is its role in the regulation of ion channels, which are involved in the rapid diffusion of sodium and potassium ions into and out of cells. Drugs that can modulate ion channels can be effective in treating a wide range of diseases, including heart failure, epilepsy, and neurodegenerative diseases.

Another potential drug target for PPIAL4E is its role in the regulation of intracellular signaling pathways. These pathways are involved in the regulation of cell growth, differentiation, and survival, and are important for the development and progression of many diseases. Drugs that can modulate intracellular Signaling pathways, such as those that target the PI3K/Akt pathway, can be effective in treating a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

In addition to its potential as a drug target, PPIAL4E is also a potential biomarker for several diseases. Its expression has been shown to be elevated in a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. This suggests that PPIAL4E may be a useful biomarker for these diseases, and that its levels may be a useful diagnostic target for these conditions.

Role as a Biomarker

PPIAL4E has been shown to be expressed in a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Its expression has been associated with the development and progression of these conditions, and it is thought to play a role in the regulation of ion channels and intracellular signaling pathways.

In addition to its potential as a drug target, PPIAL4E is also a potential biomarker for several diseases. Its expression has been shown to be elevated in a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. This suggests that PPIAL4E may be a useful biomarker for these conditions, and that its levels may be a useful diagnostic target for these conditions.

Conclusion

PPIAL4E is a protein that is expressed in human tissues and has been shown to play

Protein Name: Peptidylprolyl Isomerase A Like 4E

The "PPIAL4E Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PPIAL4E comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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