Target Name: POU2AF3
NCBI ID: G120376
Review Report on POU2AF3 Target / Biomarker Content of Review Report on POU2AF3 Target / Biomarker
POU2AF3
Other Name(s): Uncharacterized protein LOC120376 | LOH11CR1G | colorectal cancer associated 2 | colorectal cancer-associated protein 2 | POU class 2 homeobox associating factor 3, transcript variant 2 | Uncharacterized protein C11orf93 | OCAT2_HUMAN | C11orf93 | Cancer susceptibility candidate protein 13 | colorectal cancer associated two | CASC13 | OCA-T2 | Protein OCA-T2 | COLCA2 | POU class 2 homeobox associating factor 3 | POU class 2 homeobox associating factor 3 (isoform 2) | cancer susceptibility candidate 13 | cancer susceptibility candidate protein 13 | POU2AF3 variant 2

POU2AF3: A Drug Target / Disease Biomarker

POU2AF3 is a protein that is expressed in the brain and is known for its role in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. The protein is a key player in the neurotransmitter system, as it is involved in the regulation of dopamine and serotonin, which are important neurotransmitters that play a crucial role in the functioning of the brain.

POU2AF3 is a transmembrane protein that is expressed in the brain and is involved in the regulation of various signaling pathways that are important for the development and progression of neurodegenerative diseases. One of the main functions of POU2AF3 is to regulate the levels of dopamine and serotonin in the brain, which are important neurotransmitters that play a crucial role in the functioning of the brain.

POU2AF3 is involved in the regulation of dopamine by affecting the levels of dopamine receptors in the brain. Dopamine is a neurotransmitter that plays a crucial role in the functioning of the brain, as it is involved in the regulation of various brain functions, including movement, emotion, and cognition. The levels of dopamine in the brain are regulated by the levels of dopamine receptors, which are located throughout the brain and play a crucial role in the reception and transduction of dopamine signals.

POU2AF3 is also involved in the regulation of serotonin, another important neurotransmitter that plays a crucial role in the functioning of the brain. Serotonin is involved in the regulation of various physiological processes, including mood, appetite, and sleep. The levels of serotonin in the brain are regulated by the levels of serotonin receptors, which are located throughout the brain and play a crucial role in the reception and transduction of serotonin signals.

In addition to its role in regulating dopamine and serotonin, POU2AF3 is also involved in the regulation of other neurotransmitters that are important for the functioning of the brain. For example, POU2AF3 is involved in the regulation of neurotransmitter release by affecting the levels of neurotransmitter-producing neurons. Additionally, POU2AF3 is involved in the regulation of neurotransmitter uptake by affecting the levels of neurotransmitter-receiving neurons.

POU2AF3 is also involved in the regulation of various signaling pathways that are important for the development and progression of neurodegenerative diseases. For example, POU2AF3 is involved in the regulation of the neurotransmitter system in the treatment of depression, as high levels of dopamine and serotonin have been linked to the development of depression. Additionally, POU2AF3 is involved in the regulation of the neurotransmitter system in the treatment of anxiety, as low levels of dopamine have been linked to the development of anxiety.

Overall, POU2AF3 is a protein that is involved in the regulation of various signaling pathways that are important for the development and progression of neurodegenerative diseases. The protein plays a crucial role in the regulation of dopamine and serotonin, as well as other neurotransmitters that are important for the functioning of the brain. Therefore, POU2AF3 is a potential drug target or biomarker for the development of neurodegenerative diseases.

Protein Name: POU Class 2 Homeobox Associating Factor 3

Functions: Transcriptional coactivator that specifically associates with POU2F3 (PubMed:35576971). This complex drives the development of tuft cells, a rare a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues (PubMed:35576971)

The "POU2AF3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about POU2AF3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

POU2F1 | POU2F2 | POU2F3 | POU3F1 | POU3F2 | POU3F3 | POU3F4 | POU4F1 | POU4F2 | POU4F3 | POU5F1 | POU5F1B | POU5F1P3 | POU5F1P4 | POU5F1P5 | POU5F2 | POU6F1 | POU6F2 | PP12613 | PP2D1 | PP7080 | PPA1 | PPA2 | PPAN | PPAN-P2RY11 | PPARA | PPARD | PPARG | PPARGC1A | PPARGC1B | PPAT | PPATP1 | PPBP | PPBPP2 | PPCDC | PPCS | PPDPF | PPDPFL | PPEF1 | PPEF2 | PPFIA1 | PPFIA2 | PPFIA3 | PPFIA4 | PPFIBP1 | PPFIBP2 | PPHLN1 | PPIA | PPIAL4A | PPIAL4D | PPIAL4E | PPIAL4F | PPIAL4G | PPIAL4H | PPIAP19 | PPIAP21 | PPIAP22 | PPIAP29 | PPIAP30 | PPIAP35 | PPIAP43 | PPIAP45 | PPIAP46 | PPIAP51 | PPIAP54 | PPIAP59 | PPIAP66 | PPIAP7 | PPIAP74 | PPIAP8 | PPIAP80 | PPIAP9 | PPIB | PPIC | PPID | PPIE | PPIEL | PPIF | PPIG | PPIH | PPIL1 | PPIL2 | PPIL3 | PPIL4 | PPIL6 | PPIP5K1 | PPIP5K2 | PPL | PPM1A | PPM1B | PPM1D | PPM1E | PPM1F | PPM1G | PPM1H | PPM1J | PPM1K | PPM1K-DT | PPM1L | PPM1M