FBXW5: A Drug Target / Disease Biomarker (G54461)

Target Name: FBXW5

NCBI ID: G54461

FBXW5

FBXW5: A Drug Target / Disease Biomarker

FacebookeXpress Western blotting, also known as FBXW5, is a drug target and a biomarker that is used for diagnostic purposes. It is a single-chain variable fragment fragment technology that allows for the detection and quantification of specific proteins in a sample. FBXW5 has been shown to be highly sensitive and specific for the detection of a wide range of proteins, with a detection limit of 0.2ng/mL.

FBXW5 is used in a variety of diagnostic applications, including cancer, inflammation, and autoimmune disorders. In cancer, FBXW5 is often used as a marker for the diagnosis and prognosis of various types of cancer, such as breast cancer, lung cancer, and colorectal cancer. In inflammation, FBXW5 is used to assess the severity of different types of inflammation, such as mild or severe.

One of the key advantages of FBXW5 is its high sensitivity. Because it is a variable fragment, it is able to detect small changes in the concentration of a protein, even if the protein is present at a low level. This makes it a useful tool for detecting diseases that are characterized by the presence of specific proteins, such as cancer or autoimmune disorders.

FBXW5 is also highly specific for its target proteins. Because it is designed to recognize a specific variable fragment of each protein, it is able to detect only those proteins that are of interest, and not those that are present in the sample but not the target protein. This reduces the potential for false positives and ensures that the results are accurate and reliable.

In addition to its high sensitivity and specificity, FBXW5 is also relatively simple to use. It is a solid-phase assay, which means that it does not require any special equipment other than a sample, a buffer, and a reagent. This makes it easy to use in a variety of settings, including clinical laboratories, research settings, and point-of-care testing.

FBXW5 has also been shown to have several potential applications in drug development. Because it is a sensitive and specific marker for the detection of proteins, it can be used to identify potential drug targets. For example, studies have shown that FBXW5 can be used to identify potential drug targets for a variety of diseases, including cancer, neurodegenerative disorders, and autoimmune disorders.

In addition to its potential as a drug target, FBXW5 has also been shown to be a valuable biomarker for other types of analyses. For example, it has been used to assess the efficacy of different treatments in clinical trials, as well as to monitor the progress of disease in patients. In addition, FBXW5 has been shown to be a useful tool for research into the mechanisms of different diseases, including cancer, neurodegenerative disorders, and autoimmune disorders.

Overall, FBXW5 is a drug target and biomarker that has the potential to revolutionize the field of diagnostic analysis. Its high sensitivity and specificity, as well as its simple to use nature, make it an attractive tool for a variety of applications in drug development and disease diagnosis.

Protein Name: F-box And WD Repeat Domain Containing 5

Functions: Substrate recognition component of both SCF (SKP1-CUL1-F-box protein) and DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes. Substrate recognition component of the SCF(FBXW5) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SASS6 during S phase, leading to prevent centriole reduplication. The SCF(FBXW5) complex also mediates ubiquitination and degradation of actin-regulator EPS8 during G2 phase, leading to the transient degradation of EPS8 and subsequent cell shape changes required to allow mitotic progression. Substrate-specific adapter of the DCX(FBXW5) E3 ubiquitin-protein ligase complex which mediates the polyubiquitination and subsequent degradation of TSC2. May also act as a negative regulator of MAP3K7/TAK1 signaling in the interleukin-1B (IL1B) signaling pathway

The "FBXW5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FBXW5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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