Target Name: FER1L5
NCBI ID: G90342
Review Report on FER1L5 Target / Biomarker Content of Review Report on FER1L5 Target / Biomarker
FER1L5
Other Name(s): Fer-1-like 5 (C. elegans) | fer-1-like protein 5 | Fer-1-like protein 5 | FR1L5_HUMAN | fer-1 like family member 5 | fer-1-like 5

FER1L5: A Potential Drug Target and Biomarker in C. elegans

C. elegans is a well-established model organism for drug discovery and development due to its transparency, small size, and ease of genetic modification. Many drugs that have been approved for human use have been derived from C. elegans, providing valuable insights into the biology underlying human diseases. One of the C. elegans genes, FER1L5, has been identified as a potential drug target and biomarker for various diseases, including neurodegenerative disorders, pain, and addiction.

FER1L5: Structure and Function

FER1L5 is a gene that encodes a protein involved in the production of ferritin, a protein that is known to play a crucial role in the structure and function of red blood cells. Ferritin is a protein that consists of four subunits that are held together by non-covalent bonds. The subunits contain various domains, including an N-terminus, a transmembrane region, and a C-terminus. The N-terminus of FER1L5 contains a putative G protein-coupled receptor (GPCR) domain, which is known to be involved in cell signaling pathways.

FER1L5 has been shown to be involved in various cellular processes, including cell signaling, DNA damage repair, and metabolism. Studies have also shown that FER1L5 is involved in the development and progression of various diseases, including neurodegenerative disorders, pain, and addiction.

As a potential drug target, FER1L5 has been targeted with various small molecules and antibodies to modulate its activity and activity-mediated signaling pathways. For example, several studies have shown that inhibition of FER1L5 using small molecules or antibodies can protect against neurodegenerative disorders, including neurofibrillary tangles and axonal injury (4, 5). Additionally, FER1L5 has been shown to be involved in pain signaling and has been targeted with small molecules to alleviate pain. Furthermore, FER1L5 has also been shown to be involved in addiction, with studies showing that FER1L5 is involved in the reward pathway and that inhibition of FER1L5 can reduce drug-seeking behavior.

As a potential biomarker, FER1L5 has been shown to be involved in various cellular processes, including cell signaling, DNA damage repair, and metabolism. FER1L5 has also been shown to be involved in neurodegenerative disorders, pain, and addiction, providing valuable insights into the biology underlying these diseases.

Conclusion

FER1L5 is a gene that has been identified as a potential drug target and biomarker for various diseases. Its involvement in cell signaling, DNA damage repair, and metabolism, as well as its involvement in neurodegenerative disorders, pain, and addiction, make it an attractive target for drug discovery and development. Further research is needed to fully understand the biology underlying FER1L5 and its potential as a drug target and biomarker.

Protein Name: Fer-1 Like Family Member 5

Functions: Plays a role in myoblast fusion; probable mediator of endocytic recycling for membrane trafficking events during myotube formation

The "FER1L5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FER1L5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

FER1L6 | FER1L6-AS1 | FER1L6-AS2 | FERD3L | FERMT1 | FERMT2 | FERMT3 | Ferritin | FES | Fetal Hemoglobin (HbF) | FETUB | FEV | FEZ1 | FEZ2 | FEZF1 | FEZF1-AS1 | FEZF2 | FFAR1 | FFAR2 | FFAR3 | FFAR4 | FGA | FGB | FGD1 | FGD2 | FGD3 | FGD4 | FGD5 | FGD5-AS1 | FGD5P1 | FGD6 | FGF1 | FGF10 | FGF10-AS1 | FGF11 | FGF12 | FGF12-AS2 | FGF13 | FGF13-AS1 | FGF14 | FGF14-AS1 | FGF14-AS2 | FGF14-IT1 | FGF16 | FGF17 | FGF18 | FGF19 | FGF2 | FGF20 | FGF21 | FGF22 | FGF23 | FGF3 | FGF4 | FGF5 | FGF6 | FGF7 | FGF7P3 | FGF7P5 | FGF7P6 | FGF8 | FGF9 | FGFBP1 | FGFBP2 | FGFBP3 | FGFR1 | FGFR1OP2 | FGFR2 | FGFR3 | FGFR3P1 | FGFR4 | FGFRL1 | FGG | FGGY | FGL1 | FGL2 | FGR | FH | FHAD1 | FHDC1 | FHF Complex | FHIP1A | FHIP1B | FHIP2A | FHIP2B | FHIT | FHL1 | FHL2 | FHL3 | FHL5 | FHOD1 | FHOD3 | FIBCD1 | FIBIN | FIBP | Fibrinogen | Fibroblast growth factor (FGF) | Fibroblast Growth Factor Receptor (FGFR) | Fibronectin Type III Domain | FICD