Exploring the Potential Applications of DENND2A as a Drug Target or Biomarker
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Exploring the Potential Applications of DENND2A as a Drug Target or Biomarker
Abstract:
DENND2A, a protein located in the endoplasmic reticulum (ER), has been identified as a potential drug target and biomarker. Its unique structure and subcellular localization have made it an attractive target for small molecules and antibodies. This article will discuss the current research on DENND2A, its potential drug target status, and its potential as a biomarker for various diseases.
Introduction:
The endoplasmic reticulum (ER) is a complex organell
Protein Name: DENN Domain Containing 2A
Functions: Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May play a role in late endosomes back to trans-Golgi network/TGN transport
The "DENND2A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DENND2A comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
DENND2B | DENND2C | DENND2D | DENND3 | DENND4A | DENND4B | DENND4C | DENND5A | DENND5B | DENND6A | DENND6B | DENR | DEPDC1 | DEPDC1-AS1 | DEPDC1B | DEPDC4 | DEPDC5 | DEPDC7 | DEPP1 | DEPTOR | DERA | DERL1 | DERL2 | DERL3 | DES | DESI1 | DESI2 | DET1 | DEUP1 | DEXI | DFFA | DFFB | DGAT1 | DGAT2 | DGAT2L6 | DGCR11 | DGCR2 | DGCR5 | DGCR6 | DGCR6L | DGCR8 | DGKA | DGKB | DGKD | DGKE | DGKG | DGKH | DGKI | DGKK | DGKQ | DGKZ | DGKZP1 | DGLUCY | DGUOK | DGUOK-AS1 | DHCR24 | DHCR7 | DHDDS | DHDDS-AS1 | DHDH | DHFR | DHFR2 | DHFRP3 | DHH | DHODH | DHPS | DHRS1 | DHRS11 | DHRS12 | DHRS13 | DHRS2 | DHRS3 | DHRS4 | DHRS4-AS1 | DHRS4L1 | DHRS4L2 | DHRS7 | DHRS7B | DHRS7C | DHRS9 | DHRSX | DHTKD1 | DHX15 | DHX16 | DHX29 | DHX30 | DHX32 | DHX33 | DHX34 | DHX35 | DHX36 | DHX37 | DHX38 | DHX40 | DHX57 | DHX58 | DHX8 | DHX9 | DIABLO | Diacylglycerol Acyltransferase (DGAT)