Target Name: DENND11
NCBI ID: G57189
Review Report on DENND11 Target / Biomarker Content of Review Report on DENND11 Target / Biomarker
DENND11
Other Name(s): Predicted protein of HQ2561 | predicted protein of HQ2561 | protein LCHN | DENN domain containing 11 | PRO2561 | DEN11_HUMAN | KIAA1147 | OTTHUMP00000212268 | LCHN | DENN domain-containing protein 11

DENND11: A Potential Drug Target and Biomarker for the HQ2561 Pred protein

Introduction

The protein HQ2561, also known as DENND11, plays a crucial role in the regulation of cell growth, differentiation, and neurotransmission. Its unique structure and function have made it an attractive target for drug development, particularly for the treatment of neurodegenerative diseases. In this article, we will explore the potential of DENND11 as a drug target and biomarker.

Potential Drug Target

DENND11 has been shown to modulate various cellular processes that are associated with neurodegenerative diseases, including neurotransmission, synaptic plasticity, and inflammation. Its role in these processes makes it an attractive target for drug development.

One of the most promising aspects of DENND11 is its ability to modulate neurotransmission. neurotransmission is the process by which neurons transmit information between neurons, and it is critical for the function of the nervous system. DENND11 has been shown to regulate neurotransmission by modulating the release of various neurotransmitters, such as dopamine, serotonin, and nitric oxide. This modulation of neurotransmission is crucial for the survival and function of neurons, and is Therefore, a potential drug target for neurodegenerative diseases.

Another promising aspect of DENND11 is its ability to modulate synaptic plasticity. Synaptic plasticity is the ability of neurons to change and adapt in response to experience, and it is critical for the formation and maintenance of neural connections. DENND11 has been shown to modulate synaptic plasticity by regulating the release of various neurotransmitters, such as dopamine, and by modulating the activity of various signaling pathways that are involved in synaptic plasticity.

In addition to its role in modulating neurotransmission and synaptic plasticity, DENND11 has also been shown to modulate inflammation. Inflammation is a critical immune response that is necessary for the maintenance of health, but it can also contribute to the development and progression of neurodegenerative diseases. DENND11 has been shown to regulate inflammation by modulating the activity of various signaling pathways that are involved in inflammation.

Potential Biomarkers

DENND11 may also be used as a biomarker for the diagnosis and monitoring of neurodegenerative diseases. Its unique function and structure make it an attractive target for the development of new diagnostic tools and biomarkers.

One of the most promising aspects of DENND11 as a biomarker is its ability to serve as a protein target for drug development. By identifying and targeting the DENND11 protein, researchers may be able to develop new treatments for neurodegenerative diseases.

Another promising aspect of DENND11 as a biomarker is its stability and expression in various tissues. DENND11 has been shown to be expressed in a variety of tissues, including brain, heart, and muscle. This stability and expression make it an attractive target for the development of biomarkers that can be used for the diagnosis and monitoring of neurodegenerative diseases.

Conclusion

DENND11 is a protein that has the potential to be a drug target and biomarker for the treatment of neurodegenerative diseases. Its unique structure and function make it an attractive target for drug development, and its role in modulating neurotransmission, synaptic plasticity, and inflammation makes it an attractive target for the development of new diagnostic tools and biomarkers.

We look forward to future studies that will continue to explore the potential of DENND11 as a drug target and biomarker for the treatment of neurodegenerative diseases.

Protein Name: DENN Domain Containing 11

Functions: Probable guanine nucleotide exchange factor (GEF). May promote the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form (Probable). May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampus following transient cerebral ischemia (By similarity)

The "DENND11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DENND11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

DENND1A | DENND1B | DENND1C | DENND2A | DENND2B | DENND2C | DENND2D | DENND3 | DENND4A | DENND4B | DENND4C | DENND5A | DENND5B | DENND6A | DENND6B | DENR | DEPDC1 | DEPDC1-AS1 | DEPDC1B | DEPDC4 | DEPDC5 | DEPDC7 | DEPP1 | DEPTOR | DERA | DERL1 | DERL2 | DERL3 | DES | DESI1 | DESI2 | DET1 | DEUP1 | DEXI | DFFA | DFFB | DGAT1 | DGAT2 | DGAT2L6 | DGCR11 | DGCR2 | DGCR5 | DGCR6 | DGCR6L | DGCR8 | DGKA | DGKB | DGKD | DGKE | DGKG | DGKH | DGKI | DGKK | DGKQ | DGKZ | DGKZP1 | DGLUCY | DGUOK | DGUOK-AS1 | DHCR24 | DHCR7 | DHDDS | DHDDS-AS1 | DHDH | DHFR | DHFR2 | DHFRP3 | DHH | DHODH | DHPS | DHRS1 | DHRS11 | DHRS12 | DHRS13 | DHRS2 | DHRS3 | DHRS4 | DHRS4-AS1 | DHRS4L1 | DHRS4L2 | DHRS7 | DHRS7B | DHRS7C | DHRS9 | DHRSX | DHTKD1 | DHX15 | DHX16 | DHX29 | DHX30 | DHX32 | DHX33 | DHX34 | DHX35 | DHX36 | DHX37 | DHX38 | DHX40 | DHX57 | DHX58