ESD-10: A Potential Drug Target and Biomarker (G2098)

Target Name: ESD

NCBI ID: G2098

Content of Review Report on ESD Target / Biomarker

ESD

ESD-10: A Potential Drug Target and Biomarker

Esterase 10 (ESD-10) is a protein that is expressed in various cell types of the human body, including epithelial, hematopoietic, and neural cells. It is a member of the glycophospholipid (GP) family, which includes a variety of enzymes that are involved in cellular signaling and signaling pathways. One of the functions of ESD-10 is to catalyze the esterase reaction, which is the breakdown of an ester link between a phospholipid and a nucleotide. This reaction is critical for the regulation of various cellular processes, including cell signaling, inflammation, and stress responses.

DSG-1 (Dipeptidylserine) is a similar protein that is expressed in many tissues of the body and is involved in the regulation of cell signaling. It is a potent inhibitor of the protein kinase C (PKC), which is a key regulator of many cellular processes, including cell signaling, DNA replication, and stress responses. The DSG-1/PKC system is a well-established target for many drugs, including inhibitors of tyrosine kinase activity, such as gefitinib and sorafenib, which are used to treat various types of cancer.

ESD-10 and DSG-1 as drug targets

The potential drug targets for ESD-10 and DSG-1 are based on their involvement in cellular signaling pathways and their ability to regulate multiple cellular processes. One of the potential drug targets for ESD-10 is the regulation of PKC activity, which is critical for the development and progression of various diseases, including cancer.

In cancer, ESD-10 and PKC activity are often increased, which can lead to the development of cancer cell stemness and the formation of cancer stem-derived entities (CSCs). Therefore, inhibitors of ESD-10 and PKC activity could be useful for the treatment of cancer. For example, inhibitors of ESD-10 have been shown to be effective in inhibiting the growth and migration of various types of cancer cells, including breast, lung, and ovarian cancer.

In addition to its role in cancer development, ESD-10 is also involved in the regulation of cellular signaling pathways that are critical for normal cellular function. For example, ESD-10 is involved in the regulation of the formation of the cytoskeleton, which is important for the proper functioning of cells and is critical for cell signaling. Therefore, inhibitors of ESD-10 could also be useful for the treatment of various types of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In conclusion, ESD-10 is a protein that is involved in various cellular signaling pathways and is expressed in a variety of tissues of the human body. While more research is needed to fully understand the role of ESD-10 in cellular signaling pathways, its potential as a drug target for the treatment of various types of cancer and neurodegenerative diseases is significant.

Protein Name: Esterase D

Functions: Serine hydrolase involved in the detoxification of formaldehyde

The "ESD Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ESD comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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