Target Name: ESRRA
NCBI ID: G2101
Review Report on ESRRA Target / Biomarker Content of Review Report on ESRRA Target / Biomarker
ESRRA
Other Name(s): ESRL1 | estrogen related receptor alpha | ERRa | ERR1 | Estrogen-related receptor alpha | Steroid hormone receptor ERR1 (isoform 1) | ESRRA variant 2 | ESRRA variant 1 | estrogen receptor-like 1 | estrogen-related nuclear receptor alpha | NR3B1 | ERR-alpha | ERR1_HUMAN | Steroid hormone receptor ERR1 | Estrogen related receptor alpha, transcript variant 1 | nuclear receptor subfamily 3 group B member 1 | Nuclear receptor subfamily 3 group B member 1 | ERRalpha | Estrogen related receptor alpha, transcript variant 2 | Estrogen-related nuclear receptor alpha | Estrogen receptor-like 1

ESRPA: A GPCR Receptor for A Variety of Physiological Processes

ESRRA (endosulfonium saccharate receptor alpha) is a protein that is expressed in various tissues throughout the body, including the nervous system, endocrine system, and urological system. It is a G protein-coupled receptor (GPCR), which means it is a transmembrane protein that is able to interact with intracellular signaling molecules.

ESRPA is involved in a wide range of physiological processes in the body, including sensory perception, neurotransmitter signaling, and hormone regulation. It is also involved in the development and maintenance of the nervous system, as well as the regulation of inflammation and stress responses.

Due to its involvement in so many important physiological processes, ESRPA has been identified as a potential drug target. Researchers are currently studying the potential mechanisms of action of ESRPA and are exploring new ways to use it as a therapeutic agent.

One of the main reasons for the potential of ESRPA as a drug target is its widespread expression in various tissues. This makes it a promising candidate for a drug that can act on a broad range of targets. Additionally, ESRPA is known to be involved in a number of different signaling pathways, which makes it a potential target for a variety of different drugs.

Another reason for the potential of ESRPA as a drug target is its role in the development and maintenance of the nervous system. ESRPA is involved in the regulation of a wide range of neural processes, including the development and maintenance of neurons, the formation of synapses, and the regulation of neurotransmitter release.

Additionally, ESRPA is involved in the regulation of the immune system, which is another important system that is regulated by ESRPA. It is known to be involved in the regulation of immune cell function, as well as the regulation of inflammation.

Overall, ESRPA is a protein that is involved in a wide range of important physiological processes in the body. As a result, it is a promising candidate for a drug target. Further research is needed to fully understand the mechanisms of action of ESRPA and to explore its potential as a therapeutic agent.

Protein Name: Estrogen Related Receptor Alpha

Functions: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle

The "ESRRA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ESRRA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ESRRB | ESRRG | ESS2 | Estrogen receptor | Estrogen-related receptor (ERR) (nonspecifed subtype) | ESX1 | ESYT1 | ESYT2 | ESYT3 | ETAA1 | ETF1 | ETFA | ETFB | ETFBKMT | ETFDH | ETFRF1 | ETHE1 | ETNK1 | ETNK2 | ETNPPL | ETS1 | ETS2 | ETS2-AS1 | ETV1 | ETV2 | ETV3 | ETV3L | ETV4 | ETV5 | ETV6 | ETV7 | Eukaryotic translation initiation factor 2-alpha kinase | Eukaryotic translation initiation factor 2B | Eukaryotic translation initiation factor 3 (eIF-3) complex | Eukaryotic Translation Initiation Factor 4A (eIF-4A) | Eukaryotic Translation Initiation Factor 4E Binding Protein | EVA1A | EVA1A-AS | EVA1B | EVA1C | EVC | EVC2 | EVI2A | EVI2B | EVI5 | EVI5L | EVL | EVPL | EVPLL | EVX1 | EVX1-AS | EVX2 | EWSAT1 | EWSR1 | EXD1 | EXD2 | EXD3 | EXO1 | EXO5 | EXOC1 | EXOC1L | EXOC2 | EXOC3 | EXOC3-AS1 | EXOC3L1 | EXOC3L2 | EXOC3L4 | EXOC4 | EXOC5 | EXOC5P1 | EXOC6 | EXOC6B | EXOC7 | EXOC8 | Exocyst complex | EXOG | EXOGP1 | Exon junction complex | EXOSC1 | EXOSC10 | EXOSC10-AS1 | EXOSC2 | EXOSC3 | EXOSC4 | EXOSC5 | EXOSC6 | EXOSC7 | EXOSC8 | EXOSC9 | Exosome Complex | EXPH5 | EXT1 | EXT2 | EXTL1 | EXTL2 | EXTL2P1 | EXTL3 | EXTL3-AS1 | EYA1 | EYA2