Target Name: ETV2
NCBI ID: G2116
Review Report on ETV2 Target / Biomarker Content of Review Report on ETV2 Target / Biomarker
ETV2
Other Name(s): ets variant gene 2 | ETS variant transcription factor 2 | ETV2_HUMAN | ER71 | ETV2 variant 1 | ETS variant transcription factor 2, transcript variant 1 | ETS translocation variant 2 (isoform 1) | MGC129834 | Ets-related protein 71 | ETSRP71 | MGC129835 | ETS variant 2 | Ets variant gene 2 | ETS translocation variant 2 | ets-related protein 71

ETV2: A Potential Cancer Drug Target Or Biomarker

ETV2 (Ets variant gene 2) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer. ETV2 is a gene that encodes a protein known as ETV2-TIM, which is a tumor suppressor gene that has been implicated in the development and progression of various cancers.

The ETV2 gene is located on chromosome 1p36 and has been implicated in the development of many types of cancer, including breast, ovarian, and prostate cancers. Studies have shown that individuals with certain genetic variations in the ETV2 gene are at an increased risk of developing these types of cancer.

One of the most promising aspects of ETV2 is its potential as a drug target. By targeting the ETV2-TIM protein, researchers believe they may be able to inhibit its function and prevent cancer cells from developing. This could be done through a variety of methods, including adding small molecules to the ETV2-TIM protein to disrupt its function, or by using antibodies to target and remove it from cancer cells.

Another potential use of ETV2 as a drug target is its potential as a biomarker. By measuring the levels of ETV2-TIM in cancer cells, researchers may be able to monitor the effectiveness of different treatments and identify biomarkers that can indicate the success or failure of those treatments. This could be a valuable tool in the development of new cancer treatments.

In addition to its potential as a drug target or biomarker, ETV2 is also of interest to researchers because of its location on chromosome 1p36. This gene is known as a \"cancer-associated gene,\" meaning that it has been implicated in the development and progression of many types of cancer. By studying the function of ETV2, researchers may be able to gain insights into the underlying mechanisms of cancer development and potentially identify new treatments.

Overall, ETV2 is a gene that has great potential as a drug target or biomarker for the treatment of cancer. While more research is needed to fully understand its function and potential, its identification and study could lead to new and effective treatments for this deadly disease.

Protein Name: ETS Variant Transcription Factor 2

Functions: Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'

The "ETV2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ETV2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ETV3 | ETV3L | ETV4 | ETV5 | ETV6 | ETV7 | Eukaryotic translation initiation factor 2-alpha kinase | Eukaryotic translation initiation factor 2B | Eukaryotic translation initiation factor 3 (eIF-3) complex | Eukaryotic Translation Initiation Factor 4A (eIF-4A) | Eukaryotic Translation Initiation Factor 4E Binding Protein | EVA1A | EVA1A-AS | EVA1B | EVA1C | EVC | EVC2 | EVI2A | EVI2B | EVI5 | EVI5L | EVL | EVPL | EVPLL | EVX1 | EVX1-AS | EVX2 | EWSAT1 | EWSR1 | EXD1 | EXD2 | EXD3 | EXO1 | EXO5 | EXOC1 | EXOC1L | EXOC2 | EXOC3 | EXOC3-AS1 | EXOC3L1 | EXOC3L2 | EXOC3L4 | EXOC4 | EXOC5 | EXOC5P1 | EXOC6 | EXOC6B | EXOC7 | EXOC8 | Exocyst complex | EXOG | EXOGP1 | Exon junction complex | EXOSC1 | EXOSC10 | EXOSC10-AS1 | EXOSC2 | EXOSC3 | EXOSC4 | EXOSC5 | EXOSC6 | EXOSC7 | EXOSC8 | EXOSC9 | Exosome Complex | EXPH5 | EXT1 | EXT2 | EXTL1 | EXTL2 | EXTL2P1 | EXTL3 | EXTL3-AS1 | EYA1 | EYA2 | EYA3 | EYA4 | EYS | EZH1 | EZH2 | EZHIP | EZR | F10 | F11 | F11-AS1 | F11R | F12 | F13A1 | F13B | F2 | F2R | F2RL1 | F2RL2 | F2RL3 | F3 | F5 | F7 | F8 | F8A1 | F8A2