HJURP: A Key Regulator of Tissue Development and Disease (G55355)

Target Name: HJURP

NCBI ID: G55355

HJURP

HJURP: A Key Regulator of Tissue Development and Disease

HJURP (fetal liver-expressing gene 1 protein) is a protein that is expressed in the liver of fetal origin in the adult. It is a small non-coding RNA molecule that plays a critical role in the development and maintenance of tissues, particularly the liver. HJURP is a key regulator of the hematopoietic stem cell (HSC) and has been shown to play a key role in the development of various diseases, including cancer.

HJURP is expressed in the liver of fetal origin in the adult and is highly expressed in the liver, as well as other tissues, such as the heart, lungs, and pancreas. It is a small non-coding RNA molecule that is made up of only a few hundred amino acids. HJURP has been shown to play a critical role in the development and maintenance of tissues, particularly the liver.

One of the most significant functions of HJURP is its role as a regulator of the hematopoietic stem cell (HSC). HSC is a type of stem cell that is responsible for the production of all of the different blood cells in the body, including red blood cells, white blood cells, and platelets. HJURP plays a key role in the development and maintenance of HSC, as well as the proliferation and differentiation of these stem cells into different blood cells.

In addition to its role as a regulator of HSC, HJURP has also been shown to play a critical role in the development and progression of various diseases, including cancer. For example, studies have shown that high levels of HJURP are associated with an increased risk of certain types of cancer, such as liver cancer and pancreatic cancer. Additionally, HJURP has been shown to promote the growth and survival of cancer cells, which could make it an attractive drug target for cancer therapies.

Another function of HJURP is its role as a biomarker. HJURP has been shown to be expressed in a variety of tissues and has been used as a biomarker for various diseases, including cancer. For example, studies have shown that HJURP is highly expressed in the liver, which could make it an attractive biomarker for monitoring the effectiveness of cancer therapies in the liver. Additionally, HJURP has been shown to be expressed in other tissues that are commonly used as targets for drug testing, such as the heart and the brain.

Despite the potential for HJURP as a drug target or biomarker, much more research is needed to fully understand its role in these processes. For example, it is not yet clear what the full range of functions of HJURP is, or how it interacts with other molecules in the body. Additionally, there is a need for more research to determine the most effective ways to target HJURP and to develop new therapies based on these interactions.

In conclusion, HJURP is a protein that is expressed in the liver of fetal origin in the adult and plays a critical role in the development and maintenance of tissues, particularly the liver. HJURP is a key regulator of the hematopoietic stem cell (HSC) and has been shown to play a key role in the development and progression of various diseases, including cancer. Additionally, HJURP has also been shown to be a biomarker for these diseases and could be a valuable tool for the development of new therapies. Further research is needed to fully understand the full range of functions of HJURP and to develop new therapies based on these interactions.

Protein Name: Holliday Junction Recognition Protein

Functions: Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions

The "HJURP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HJURP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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