Target Name: PARVA
NCBI ID: G55742
Review Report on PARVA Target / Biomarker Content of Review Report on PARVA Target / Biomarker
PARVA
Other Name(s): Alpha-parvin | Matrix-remodeling-associated protein 2 | parvin alpha | FLJ10793 | Actopaxin | Parvin alpha | matrix-remodeling-associated protein 2 | calponin-like integrin-linked kinase-binding protein | MXRA2 | PARVA_HUMAN | actopaxin | FLJ12254 | CH-ILKBP | Calponin-like integrin-linked kinase-binding protein | Matrix-remodelling associated 2

PARVA: The Potential Drug Target of Alpha-Parvin

Alpha-parvin is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of cell growth and differentiation, and its levels have been linked to a number of diseases, including cancer. As a result, targeting alpha-parvin has become an attractive target for drug development in a variety of therapeutic areas. In this article, we will explore the potential drug target of alpha-parvin and its potential as a therapeutic drug.

The Alpha-Parvin Protein

Alpha-parvin is a 25kDa transmembrane protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of cell growth and differentiation, and its levels have been linked to a number of diseases, including cancer. The alpha-parvin protein is composed of 115 amino acid residues and has a calculated pI of 9.65. It is expressed in the brain, heart, and kidneys, and its levels have been shown to be elevated in a variety of diseases, including cancer.

The Role of Alpha-Parvin in Cellular Differentiation

Alpha-parvin plays a critical role in the regulation of cellular differentiation. It is a key regulator of the G1/S transition, which is the process by which cells prepare for cell division. The G1/S transition is a critical step in the cell cycle and is characterized by the production of RNAi, which is a protein that inhibits the activity of specific genes. Alpha-parvin promotes the production of RNAi by activating the G1-specific transcription factor p21, which is a key regulator of the G1/S transition.

The Alpha-Parvin Protein in Cancer

The alpha-parvin protein has been linked to a number of diseases, including cancer. It has been shown to be elevated in a variety of cancer tissues, including breast, ovarian, and prostate cancer. In addition, alpha-parvin has been shown to be involved in the regulation of cell cycle progression and has been linked to the development of resistance to chemotherapy.

The Potential therapeutic uses of Alpha-Parvin

The potential therapeutic uses of alpha-parvin are vast and varied. As a drug target, it has the potential to be used to treat a variety of diseases, including cancer. By inhibiting the activity of alpha-parvin, drugs can target the regulation of cell growth and differentiation, which can lead to the inhibition of the development and progression of cancer. In addition, alpha-parvin has been shown to be involved in the regulation of the cell cycle, which has the potential to be used to treat a variety of disorders, including neurodegenerative diseases.

Conclusion

In conclusion, the alpha-parvin protein has the potential to be a drug target in a variety of therapeutic areas. Its role in the regulation of cellular differentiation and its involvement in the regulation of the cell cycle make it an attractive target for drug development. Further research is needed to fully understand the potential therapeutic uses of alpha-parvin and to develop safe and effective drugs that can target this protein.

Protein Name: Parvin Alpha

Functions: Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development (By similarity). Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishment of cell polarity, cell adhesion, cell spreading, and directed cell migration

The "PARVA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PARVA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PARVB | PARVG | Parvovirus initiator complex | PASD1 | PASK | Patatin-like phospholipase domain-containing protein | PATE1 | PATE2 | PATE3 | PATE4 | PATJ | PATL1 | PATL2 | PATZ1 | PAUPAR | PAWR | PAX1 | PAX2 | PAX3 | PAX4 | PAX5 | PAX6 | PAX6-AS1 | PAX7 | PAX8 | PAX8-AS1 | PAX9 | PAXBP1 | PAXBP1-AS1 | PAXIP1 | PAXIP1-AS2 | PAXIP1-DT | PAXX | PBDC1 | PBK | PBLD | PBOV1 | PBRM1 | PBX1 | PBX2 | PBX3 | PBX3-DT | PBX4 | PBXIP1 | PC | PCA3 | PCAF complex | PCARE | PCAT1 | PCAT14 | PCAT18 | PCAT19 | PCAT2 | PCAT29 | PCAT4 | PCAT5 | PCAT6 | PCAT7 | PCBD1 | PCBD2 | PCBP1 | PCBP1-AS1 | PCBP2 | PCBP2-OT1 | PCBP2P2 | PCBP3 | PCBP3-AS1 | PCBP4 | PCCA | PCCA-DT | PCCB | PCDH1 | PCDH10 | PCDH11X | PCDH11Y | PCDH12 | PCDH15 | PCDH17 | PCDH18 | PCDH19 | PCDH20 | PCDH7 | PCDH8 | PCDH9 | PCDH9-AS3 | PCDH9-AS4 | PCDHA1 | PCDHA10 | PCDHA11 | PCDHA12 | PCDHA13 | PCDHA14 | PCDHA2 | PCDHA3 | PCDHA4 | PCDHA5 | PCDHA6 | PCDHA7 | PCDHA8 | PCDHA9