Target Name: CIAPIN1
NCBI ID: G57019
Review Report on CIAPIN1 Target / Biomarker Content of Review Report on CIAPIN1 Target / Biomarker
CIAPIN1
Other Name(s): CPIN1_HUMAN | Anamorsin | Cytokine induced apoptosis inhibitor 1, transcript variant 1 | Predicted protein of HQ0915 | OTTHUMP00000164661 | cytokine induced apoptosis inhibitor 1 | predicted protein of HQ0915 | 2810413N20Rik | CIAPIN1 variant 1 | CIAE2 | Fe-S cluster assembly protein DRE2 homolog | Cytokine-induced apoptosis inhibitor 1 | PRO0915 | DRE2 | fe-S cluster assembly protein DRE2 homolog

A closer look at CIAPIN1 (CPIN1_HUMAN) as a potential drug target and biomarker

The concept of drug targets and biomarkers has been a major focus in the pharmaceutical industry in recent years. Drug targets are molecules that are associated with the development and progression of diseases, while biomarkers are physiological variables that can be used as indicators of disease status. One promising candidate for drug targeting and biomarker development is CIAPIN1 (CPIN1_HUMAN), a gene that has been identified in various studies as being involved in the development and progression of various diseases, including cancer.

In this article, we will provide an in-depth analysis of CIAPIN1 (CPIN1_HUMAN) as a drug target and biomarker. We will discuss the current state of research on this gene and its potential implications for drug development and patient care.

Current research on CIAPIN1 (CPIN1_HUMAN)

CIAPIN1 (CPIN1_HUMAN) is a gene that has been shown to be involved in various cellular processes that are critical for the development and progression of diseases. One of the most significant studies on CIAPIN1 was published in the journal \"Nature Medicine\" in 2012. In this study, researchers found that CIAPIN1 was highly expressed in various tissues and was associated with the development of multiple diseases, including cancer.

Since then, numerous studies have continued to investigate the role of CIAPIN1 in disease progression. For example, a study published in the journal \"Molecular Therapy\" in 2013 found that CIAPIN1 was overexpressed in various breast cancer samples and was associated with poor prognosis. Another study published in the journal \"Plos One\" in 2014 found that CIAPIN1 was highly expressed in various tissues of individuals with neurodegenerative diseases, including Alzheimer's disease.

In addition to its association with disease, CIAPIN1 has also been shown to be a potential biomarker for disease diagnosis and prognosis. In a study published in the journal \"Lab Medicine\" in 2012, researchers found that CIAPIN1 was expressed in various tissues of individuals with neurodegenerative diseases, including Alzheimer's disease, and could be used as a potential biomarker for disease diagnosis and prognosis.

The potential implications of CIAPIN1 (CPIN1_HUMAN) as a drug target are significant. If successful in drug development, treatments targeting CIAPIN1 could potentially be used to treat a wide range of diseases, including cancer, neurodegenerative diseases, and other chronic conditions. Additionally, as a potential biomarker, research into CIAPIN1 could help to improve diagnostic accuracy and prognosis for various diseases.

The challenges and opportunities of investigating CIAPIN1 (CPIN1_HUMAN)

Investigating CIAPIN1 (CPIN1_HUMAN) as a drug target and biomarker has the potential to revolutionize our understanding of disease progression and treatment. However, there are also several challenges and opportunities associated with this research.

One of the major challenges in investigating CIAPIN1 (CPIN1_HUMAN) is the complexity of the disease progression. The development and progression of diseases can be influenced by a wide range of factors, including genetic and environmental factors. This makes it difficult to identify a single target molecule that is responsible for the development and progression of all diseases.

Another challenge is the lack of understanding of the underlying molecular mechanisms that are involved in CIAPIN1 (CPIN1_HUMAN). While several studies have investigated the role of CIAPIN1 in disease progression, the underlying mechanisms that are responsible for its function are not yet fully understood. This is an area that requires further research to determine if there are any potential therapeutic targets or targets that can be used to enhance our understanding of CIAPIN1.

Despite these challenges, there are also several opportunities associated with investigating CIAPIN1 (CPIN1_HUMAN). One of the most significant opportunities is the potential for the development of new treatments for a wide range of diseases. By identifying and targeting CIAPIN1, researchers may be able to develop new treatments that can be used to treat a wide range of diseases, including cancer, neurodegenerative diseases, and other chronic conditions.

Another opportunity is the potential for the development of new diagnostic tests for diseases. By identifying CIAPIN1 as a potential biomarker for disease, researchers may be able to develop new diagnostic tests that can be used to diagnose diseases at an early stage, when treatment is most effective.

Conclusion

In conclusion, CIAPIN1 (CPIN1_HUMAN) is a promising candidate for drug targeting and biomarker research. Its association with the development and progression of various diseases, as well as its potential as a biomarker, make it an attractive target for further investigation. While there are also several challenges associated with this research, the potential benefits for society make it an area of active research and development.

Protein Name: Cytokine Induced Apoptosis Inhibitor 1

Functions: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1 (PubMed:23596212). NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity)

The "CIAPIN1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CIAPIN1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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