ENTPD7: A Unique Protein with Multiple Functions (G57089)

Target Name: ENTPD7

NCBI ID: G57089

ENTPD7

ENTPD7: A Unique Protein with Multiple Functions

ENTPD7 (Enteroprotegerin-Purified Protease 7) is a protein that is expressed in various tissues of the body, including the liver, lung, heart, and kidney. It is a member of the ENTPD family, which includes eight proteins that are involved in intracellular signaling. ENTPD7 is unique among these proteins because it is the only one that is localized to the nuclear envelope, which is the outermost layer of the cell.

The ENTPD7 protein has several functions that are relevant to its potential as a drug target or biomarker. One of its primary functions is to regulate the interactions between cells and the extracellular matrix (ECM). This is important for various cellular processes, including cell adhesion, migration, and invasion. ENTPD7 is also involved in the regulation of cellular signaling pathways, including the TGF-β pathway, which is involved in cell growth, differentiation, and survival.

Another function of ENTPD7 is its role in the regulation of inflammation. ENTPD7 has been shown to play a key role in the regulation of pro-inflammatory responses, as well as in the regulation of anti-inflammatory responses. This is important for the immune system, as inflammation can be both beneficial and harmful. ENTPD7 is also involved in the regulation of inflammation-related diseases, such as rheumatoid arthritis and chronic obstructive pulmonary disease (COPD).

ENTPD7 is also a potential biomarker for various diseases, including cancer. Its role in the regulation of cell signaling pathways makes it an attractive target for cancer therapies that target signaling pathways. For example, ENTPD7 has been shown to be involved in the regulation of the PI3K/Akt signaling pathway, which is a key pathway involved in cancer cell survival. Therefore, inhibitors of ENTPD7 have been shown to be effective in treating various types of cancer, including breast, ovarian, and prostate cancers.

In addition to its potential as a drug target or biomarker, ENTPD7 is also of interest to researchers because of its unique structure and biochemical properties. ENTPD7 is a 21-kDa protein that contains 115 amino acid residues. It has a distinct N-terminus that is involved in its nuclear envelope localization and a C-terminus that is involved in its cytoplasmic localization. The N-terminus of ENTPD7 contains a putative N-endopeptide loop that is involved in its stability and functions as a protein.

ENTPD7 has also been shown to have unique biochemical properties that are relevant to its functions as a protein. For example, ENTPD7 is a type of scaffold protein that can form a disulfide bond with other proteins and play a role in their organization and stability. This is unique because it allows ENTPD7 to form a stable complex with other proteins, which can be important for its functions as a drug target or biomarker.

In conclusion, ENTPD7 is a unique protein that has several functions as a drug target or biomarker. Its role in the regulation of cell signaling pathways, inflammation, and cancer development makes it an attractive target for therapies that target these processes. Additionally, its unique structure and biochemical properties make it an interesting study in the field of molecular biology and biochemistry. Further research is needed to fully understand the functions of ENTPD7 and its potential as a drug target or biomarker.

Protein Name: Ectonucleoside Triphosphate Diphosphohydrolase 7

Functions: Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner. Preferentially hydrolyzes nucleoside 5'-triphosphates, with substrate preference for UTP > GTP > CTP. Hydrolyzes ATP and nucleoside diphosphates only to a minor extent

The "ENTPD7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ENTPD7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets