ENTREP1: A Protein That Helps Maintain Brain Barrier Integrity

Target Name: ENTREP1

NCBI ID: G9413

ENTREP1

ENTREP1: A Protein That Helps Maintain Brain Barrier Integrity

ENTREP1 (X123) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the ENTREP family, which includes proteins that are involved in the formation of tight junctions, which are specialized barriers that help to maintain the integrity of tissues.

One of the key functions of ENTREP1 is its role in maintaining the integrity of the blood-brain barrier. This barrier is responsible for ensuring that the brain is able to protect itself from harmful substances, and it is also involved in the transport of nutrients and oxygen to the brain. ENTREP1 helps to regulate the formation of new blood vessels in the brain, which is important for ensuring that the brain has access to the necessary oxygen and nutrients.

In addition to its role in maintaining the blood-brain barrier, ENTREP1 is also involved in the regulation of ion and water transport in the body. This protein helps to control the movement of ions and water molecules across the membrane of various tissues, which is important for maintaining the proper functioning of these tissues.

ENTREP1 is also involved in the regulation of the growth and development of various tissues in the body. This protein helps to control the formation of new tissues, as well as the growth and development of existing tissues. This is important for ensuring that the body is able to maintain its integrity and function properly.

Despite its involvement in a wide range of important functions, ENTREP1 is not yet a well-studied protein. There are currently very few studies that have focused on ENTREP1, and many of these studies are still in the early stages of research. This is because ENTREP1 is a relatively small protein, and it is difficult to study due to its small size and the challenges that are associated with studying proteins in the brain.

However, based on the studies that have been done so far, it is clear that ENTREP1 is an important protein that plays a critical role in the functioning of the body. As more research is done on this protein, it is likely to be found to have a wide range of potential applications in the treatment of various diseases. For example, ENTREP1 may be a drug target (or biomarker) that can be used to treat a variety of conditions, including neurological and cardiovascular diseases.

Protein Name: Endosomal Transmembrane Epsin Interactor 1

Functions: Functions as an activator of the E3 ubiquitin protein ligase ITCH in the ubiquitination of the CXCL12-activated CXCR4 receptor. Thereby, triggers CXCR4 endocytosis and desensitization, negatively regulating the CXCL12/CXCR4 signaling pathway

The "ENTREP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ENTREP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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