Target Name: PSME1
NCBI ID: G5720
Review Report on PSME1 Target / Biomarker Content of Review Report on PSME1 Target / Biomarker
PSME1
Other Name(s): 11S regulator complex alpha subunit | PSME1_HUMAN | HEL-S-129m | epididymis secretory sperm binding protein Li 129m | interferon-gamma IEF SSP 5111 | IFI5111 | Proteasome activator subunit 1, transcript variant 1 | 29-kD MCP activator subunit | Proteasome activator complex subunit 1 (isoform 1) | Proteasome activator 28 subunit alpha | PA28a | activator of multicatalytic protease subunit 1 | REGalpha | Proteasome activator complex subunit 1 | REG-alpha | interferon gamma up-regulated I-5111 protein | PA28A | Interferon-gamma-inducible protein 5111 | Activator of multicatalytic protease subunit 1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | IGUP I-5111 | PA28alpha | PSME2 | proteasome activator subunit 1 | 11S regulator complex subunit alpha | Interferon gamma up-regulated I-5111 protein | interferon-gamma-inducible protein 5111 | PSME1 variant 1

The PSME1 Alpha Subunit: Regulation of Plant Gene Expression

The PSME1 (11S regulator complex alpha subunit) is a protein that plays a critical role in the regulation of gene expression in plants. It is a member of the RNA-protein scaffold family and is responsible for the assembly and stability of the 11S regulatory complex , which is a protein-protein interaction network that plays a central role in the regulation of various cellular processes in plants.

The 11S regulatory complex is composed of several proteins that interact with one another to regulate gene expression. The alpha subunit of PSME1 is one of the key proteins that forms the core of the complex. It is a 21 kDa protein that consists of 115 amino acid residues.

The alpha subunit of PSME1 is involved in several different cellular processes in plants. One of its primary functions is to regulate the expression of genes that are involved in cell wall formation. The cell wall is a complex structure that is responsible for providing structural support and integrity to the cell. The genes that are involved in cell wall formation are critical for the development and maintenance of a healthy cell wall. The alpha subunit of PSME1 helps to regulate the expression of these genes by interacting with them and preventing them from being translated into protein.

Another function of the alpha subunit of PSME1 is to regulate the expression of genes that are involved in photosynthesis. The alpha subunit of PSME1 is involved in the regulation of the expression of the pigment biosynthesis gene, which is critical for the production of the pigment ink Leaf element, which is responsible for the coloration of the plant.

The alpha subunit of PSME1 is also involved in the regulation of the expression of genes that are involved in cell division and cell growth. It helps to regulate the expression of the cell division gene, which is critical for the development and growth of the cell.

In addition to its role in regulating the expression of genes involved in cell wall formation, photosynthesis, and cell division, the alpha subunit of PSME1 is also involved in the regulation of gene expression that is not directly related to these processes. For example, the alpha subunit of PSME1 has been shown to play a role in the regulation of seed germination and the Initiation of flowering (IGF2).

Despite its involvement in several different cellular processes, the alpha subunit of PSME1 is well characterized and is widely studied. It is known to interact with several different proteins, including the transcription factor TFAP2 and the protein that plays a role in the regulation of DNA methylation ,DNMT.

In addition to its role in regulating gene expression, the alpha subunit of PSME1 is also of interest as a potential drug target. Many studies have suggested that the alpha subunit of PSME1 may be a useful target for the development of new plant diseases. For example , the alpha subunit of PSME1 has been shown to play a role in the regulation of the production of the toxic compound, Ashby's blue, which is commonly used as a pesticide to kill pests.

In addition, the PSME1 gene is closely related to a variety of diseases and biochemical processes in plants. By regulating the expression of many genes, PSME1 plays an important role in plant growth, development, morphology and physiological characteristics. Therefore, PSME1 is considered an important target in plant molecular biology and drug research.

Protein Name: Proteasome Activator Subunit 1

Functions: Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome

The "PSME1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PSME1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PSME2 | PSME2P2 | PSME2P3 | PSME3 | PSME3IP1 | PSME4 | PSMF1 | PSMG1 | PSMG1-PSMG2 heterodimer | PSMG2 | PSMG3 | PSMG3-AS1 | PSMG4 | PSORS1C1 | PSORS1C2 | PSORS1C3 | PSPC1 | PSPH | PSPHP1 | PSPN | PSRC1 | PSTK | PSTPIP1 | PSTPIP2 | PTAFR | PTAR1 | PTBP1 | PTBP2 | PTBP3 | PTCD1 | PTCD2 | PTCD3 | PTCH1 | PTCH2 | PTCHD1 | PTCHD1-AS | PTCHD3 | PTCHD3P1 | PTCHD3P2 | PTCHD4 | PTCRA | PTCSC2 | PTCSC3 | PTDSS1 | PTDSS2 | PTEN | PTENP1 | PTENP1-AS | PTER | PTF1A | PTGDR | PTGDR2 | PTGDS | PTGER1 | PTGER2 | PTGER3 | PTGER4 | PTGER4P2-CDK2AP2P2 | PTGES | PTGES2 | PTGES2-AS1 | PTGES3 | PTGES3L | PTGES3L-AARSD1 | PTGES3P1 | PTGES3P2 | PTGES3P3 | PTGFR | PTGFRN | PTGIR | PTGIS | PTGR1 | PTGR2 | PTGR3 | PTGS1 | PTGS2 | PTH | PTH1R | PTH2 | PTH2R | PTK2 | PTK2B | PTK6 | PTK7 | PTMA | PTMAP1 | PTMAP5 | PTMAP7 | PTMS | PTN | PTOV1 | PTOV1-AS1 | PTOV1-AS2 | PTP4A1 | PTP4A1P2 | PTP4A2 | PTP4A3 | PTPA | PTPDC1 | PTPMT1