PSPH: A Transmembrane Protein Involved in Neurodegenerative Disorders and Cancer

Target Name: PSPH

NCBI ID: G5723

PSPH

PSPH: A Transmembrane Protein Involved in Neurodegenerative Disorders and Cancer

Phosphatidylserine (PS) is a phospholipid that is synthesized in the cytoplasm of all living cells. It is a major component of the cell membrane and plays a crucial role in various cellular processes such as signal transduction, protein targeting, and cell signaling. PS is also an important biomarker for certain diseases, including neurodegenerative disorders.

The Outer Transmembrane Proteins (OTTHUMP00000209327) are a family of proteins that are characterized by their ability to form a transmembrane channel. This allows these proteins to regulate the movement of molecules into and out of the cell, as well as to regulate the signaling processes that occur within the cell.

One of the proteins within the OTTHUMP00000209327 family is PSPH. PSPH is a 21 kDa protein that is synthesized in the cytoplasm of all living cells. It is highly conserved, with a calculated pI of 6.5. PSPH is expressed in a variety of tissues and cells, including brain, heart, and muscle.

PSPH is involved in various cellular processes, including intracellular signaling, protein transport, and intracellular signaling. It has been shown to play a role in a variety of neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease.

PSPH is also a potential drug target for several diseases. For example, PSPH has been shown to be involved in the development and progression of neurodegenerative disorders. Additionally, PSPH has been shown to play a role in the development of certain types of cancer.

In addition to its potential clinical applications, PSPH is also of interest to researchers because of its well- conserved nature. This allows researchers to study the mechanisms of its function and to develop new therapeutic strategies.

Conclusion

PSPH is a protein that is characterized by its ability to form a transmembrane channel. It is synthesized in the cytoplasm of all living cells and is involved in various cellular processes, including intracellular signaling and protein transport. PSPH has been shown to play a role in the development and progression of neurodegenerative disorders, as well as in the development of certain types of cancer.

Because of its well- conserved nature, PSPH is of interest to researchers as a potential drug target for several diseases. Further research is needed to fully understand the mechanisms of PSPH's function and to develop new therapeutic strategies.

Protein Name: Phosphoserine Phosphatase

Functions: Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine (PubMed:12213811, PubMed:15291819, PubMed:9222972, PubMed:14673469, PubMed:25080166). L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neuromodulator (PubMed:14673469). May also act on O-phospho-D-serine (Probable)

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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