Target Name: MRTFB
NCBI ID: G57496
Review Report on MRTFB Target / Biomarker Content of Review Report on MRTFB Target / Biomarker
MRTFB
Other Name(s): MRTFB_HUMAN | Myocardin-related transcription factor B | NPD001 | DKFZp686J1745 | MKL/myocardin-like protein 2 | MRTFB variant 2 | MKL/myocardin like 2 | MRTF-B | MKL1/myocardin like 2 | FLJ45623 | MKL and myocardin family member 2 | Myocardin-related transcription factor B (isoform 2) | Megakaryoblastic leukemia 2 | FLJ31823 | MKL2 | KIAA1243 | myocardin related transcription factor B | megakaryoblastic leukemia 2 | CTA-276F8.1 | Myocardin related transcription factor B, transcript variant 2

Understanding The Role of MRTFB in Cellular Processes and Its Potential as A Drug Target

MRTFB (MRTFB_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, and liver. It is a member of the superfamily of transmembrane protein (SMP) and is characterized by the presence of a transmembrane domain and a cytoplasmic tail.

The exact function of MRTFB is not yet well understood, but it is believed to play a role in the regulation of various cellular processes that are involved in the development and maintenance of tissues. It is also suggested to be involved in the regulation of inflammation and may be a potential drug target.

One of the key functions of MRTFB is its role in the regulation of cell adhesion. Adhesion is the process by which cells stick together to form tissues and organs, and it is a critical aspect of tissue development and maintenance. MRTFB is known to be involved in the regulation of adhesion by interacting with several different proteins, including cadherins and immunoglobulin adhesion molecules (Ig-CAMs).

In addition to its role in cell adhesion, MRTFB is also involved in the regulation of cell survival. It has been shown to play a role in the regulation of cell cycle progression, and to contribute to the maintenance of cellular stability. This is important for the regulation of cell growth and the prevention of cell death, as well as for the development and maintenance of tissues.

Another function of MRTFB is its role in the regulation of cellular signaling pathways. It is a known to be involved in several signaling pathways, including the TGF-β pathway and the Wnt pathway. TGF-β is a well-known signaling pathway that is involved in the regulation of cell growth, differentiation, and inflammation. The TGF-β pathway is a critical pathway in the regulation of cell behavior and has been implicated in the development of many diseases, including cancer. MRTFB is thought to be involved in the regulation of TGF-β pathway by interacting with its downstream effector, Smad2.

In addition to its role in cellular signaling pathways, MRTFB is also suggested to be involved in the regulation of inflammation. It has been shown to play a role in the regulation of immune cell function, and to contribute to the development of inflammatory diseases. This is important for the regulation of innate immune responses and the development of autoimmune diseases.

Due to its involvement in several cellular processes, MRTFB is a potential drug target. The development of compounds that can modulate the activity of MRTFB may have therapeutic applications in a variety of diseases, including cancer, autoimmune diseases, and developmental disorders. Additionally, the study of MRTFB as a drug target may also provide insight into the regulation of cell adhesion and the regulation of cellular signaling pathways.

In conclusion, MRTFB is a protein that is expressed in various tissues of the human body and is involved in several cellular processes, including cell adhesion, cell survival, and cellular signaling pathways. Its function is not yet well understood, but it is thought to play a role in the regulation of various cellular processes that are involved in the development and maintenance of tissues. Additionally, MRTFB is a potential drug target and the study of its regulation may provide insight into the regulation of cell adhesion and cellular signaling pathways. Further research is needed to fully understand the function of MRTFB and its potential as a drug target.

Protein Name: Myocardin Related Transcription Factor B

Functions: Acts as a transcriptional coactivator of serum response factor (SRF). Required for skeletal myogenic differentiation

The "MRTFB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MRTFB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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