Study on The Function and Mechanism of FNDC3B in Neurodegenerative Diseases

Target Name: FNDC3B

NCBI ID: G64778

FNDC3B

Study on The Function and Mechanism of FNDC3B in Neurodegenerative Diseases

FNDC3B, also known as FLJ23399, is a protein that is expressed in various tissues of the body, including the brain, heart, and gastrointestinal tract. It is a member of the fenolipid domain-containing G protein-coupled receptor (FGFR) family, which is a subfamily of the G protein-coupled receptor (GPCR) family. The gene products of the GPCR family include many transcription factors, hormones, neurotransmitter receptors, etc., which regulate body growth and development, metabolism, immune response, pain perception, etc. play an important role.

FNDC3B is an intracellular protein whose function is being intensively studied. Research shows that FNDC3B plays a key role in the growth, differentiation and synapse formation of neurons. During development, FNDC3B plays an important role in neuronal survival and synapse formation. In addition, FNDC3B is also related to neuronal apoptosis, so it is of great significance for understanding the pathogenesis of neuronal diseases.

The expression level of FNDC3B also plays an important role in some diseases. For example, studies have found that the expression level of FNDC3B is positively correlated with the prognosis of thyroid cancer, breast cancer, lung cancer and other cancers. In addition, the expression level of FNDC3B is closely related to the pathogenesis of neurological diseases such as Alzheimer's disease and Parkinson's disease. Therefore, studying the biological function and mechanism of action of FNDC3B is of great significance for the development of new drugs and treatment options.

In addition, FNDC3B is also considered a potential target for the treatment of some neurological diseases. For example, some researchers have found that FNDC3B can protect neurons by inhibiting neuronal apoptosis, and thus may become a potential drug target for the treatment of neurodegenerative diseases (such as Parkinson's disease, Alzheimer's disease, etc.). In addition, FNDC3B can also be used as a biomarker to detect the function and survival status of neurons, providing important basis for neuroscience research and clinical diagnosis.

In summary, FNDC3B is a protein with important biological functions, which plays a key role in neuronal growth, differentiation and apoptosis, as well as the occurrence of neurodegenerative diseases. Through in-depth study of the biological functions and mechanisms of action of FNDC3B, it is expected to discover new drugs and treatment options, which will bring good news to human health.

Protein Name: Fibronectin Type III Domain Containing 3B

Functions: May be a positive regulator of adipogenesis

The "FNDC3B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FNDC3B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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