Target Name: BTF3
NCBI ID: G689
Review Report on BTF3 Target / Biomarker Content of Review Report on BTF3 Target / Biomarker
BTF3
Other Name(s): BETA-NAC | basic transcription factor 3 | BTF3b | NAC-beta | Nascent polypeptide-associated complex subunit beta | nascent-polypeptide-associated complex beta polypeptide | BTF3_HUMAN | Transcription factor BTF3 | Transcription factor BTF3 (isoform A) | Basic transcription factor 3, transcript variant 1 | NACB | OTTHUMP00000128197 | Nascent-polypeptide-associated complex beta polypeptide | BTF3a | RNA polymerase B transcription factor 3 | BTF3 variant 1 | nascent polypeptide-associated complex subunit beta

BTF3: A Potential Drug Target for Neurological Disorders

BTF3 (BETA-NAC), a protein that is expressed in a variety of tissues throughout the body, has been identified as a potential drug target or biomarker. BTF3 is a key regulator of the nervous system, and its dysfunction has been linked to a number of neurological and psychiatric disorders.

The BTF3 gene is located on chromosome 12q13 and has been shown to encode a protein that is involved in the development and maintenance of the nervous system. The protein encoded by the BTF3 gene is composed of 258 amino acids and has been shown to play a role in the development and organization of the nervous system.

Studies have shown that BTF3 is involved in the regulation of a number of important neural processes, including cell survival, differentiation, and synaptic formation. It has been shown to play a role in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, as well as in the regulation of psychiatric disorders, such as depression and anxiety.

In addition to its role in the nervous system, BTF3 has also been shown to play a role in the regulation of inflammation and immune response. It has been shown to play a role in the regulation of T cell development and function, as well as in the regulation of inflammation in the brain.

Given its involvement in a number of important biological processes, BTF3 has potential as a drug target or biomarker. Studies have shown that BTF3 can be targeted with small molecules, such as those that inhibit its activity as a regulator of the nervous system. In addition, BTF3 has been shown to be involved in the regulation of a number of signaling pathways, including the TGF-β pathway, which is involved in the regulation of cell growth and differentiation. This suggests that BTF3 may be a useful target for the development of new therapeutic approaches for a variety of neurological and psychiatric disorders.

While further research is needed to fully understand the role of BTF3 in the nervous system and its potential as a drug target or biomarker, its potential as a therapeutic target is an exciting area of research that has the potential to lead to new treatments for a variety of neurological and psychiatric disorders.

Protein Name: Basic Transcription Factor 3

Functions: When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription

The "BTF3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about BTF3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

BTF3L4 | BTF3P11 | BTF3P7 | BTF3P9 | BTG1 | BTG2 | BTG2-DT | BTG3 | BTG4 | BTK | BTLA | BTN1A1 | BTN2A1 | BTN2A2 | BTN2A3P | BTN3A1 | BTN3A2 | BTN3A3 | BTNL10P | BTNL2 | BTNL3 | BTNL8 | BTNL9 | BTRC | BUB1 | BUB1B | BUB1B-PAK6 | BUB3 | BUD13 | BUD23 | BUD31 | Butyrophilin | Butyrophilin subfamily 3 member A (BTN3A) | BVES | BVES-AS1 | BYSL | BZW1 | BZW1-AS1 | BZW1P2 | BZW2 | C-C chemokine receptor | C10orf105 | C10orf113 | C10orf120 | C10orf126 | C10orf143 | C10orf53 | C10orf55 | C10orf62 | C10orf67 | C10orf71 | C10orf71-AS1 | C10orf82 | C10orf88 | C10orf88B | C10orf90 | C10orf95 | C10orf95-AS1 | C11orf16 | C11orf21 | C11orf24 | C11orf40 | C11orf42 | C11orf52 | C11orf54 | C11orf58 | C11orf65 | C11orf68 | C11orf71 | C11orf80 | C11orf86 | C11orf87 | C11orf91 | C11orf96 | C11orf97 | C11orf98 | C12orf29 | C12orf4 | C12orf40 | C12orf42 | C12orf43 | C12orf50 | C12orf54 | C12orf56 | C12orf57 | C12orf60 | C12orf74 | C12orf75 | C12orf76 | C13orf42 | C13orf46 | C14orf119 | C14orf132 | C14orf178 | C14orf180 | C14orf28 | C14orf39 | C14orf93 | C15orf32 | C15orf39