Unveiling the Potential of TUBAP2 as a Drug Target and Biomarker

Target Name: TUBAP2

NCBI ID: G399942

TUBAP2

Other Name(s): Tubulin, alpha pseudogene 2 | tubulin alpha pseudogene 2

Unveiling the Potential of TUBAP2 as a Drug Target and Biomarker

Introduction

Tubulin, alpha pseudogene 2 (TUBAP2) is a protein that plays a critical role in the structure and function of microtubules, which are essential components of the cytoskeleton in eukaryotic cells. TUBAP2 is a 21-kDa protein that is highly conserved across various species, including humans. It is composed of two unique domains: an N-terminal alpha-helical domain and a C-terminal T-loop domain. The N-terminal domain is responsible for the protein's unique alpha-helical structure , which is crucial for its stability and functions. The C-terminal domain is known for its role in intercalation of the alpha-tubulin protein, as well as its interaction with microtubule-associated proteins.

Several studies have identified TUBAP2 as a potential drug target and biomarker in various diseases, including cancer (5), neurodegenerative diseases (6), and autoimmune disorders. In this article, we will delve into the current understanding of TUBAP2, its potential drug targets, and its potential as a biomarker for various diseases.

Potential Drug Targets

TUBAP2 has been identified as a potential drug target due to its unique structure and its involvement in various cellular processes. One of the primary targets of TUBAP2 is the regulation of microtubule dynamics and stability. Microtubules play a crucial role in the transport of various cellular molecules, including proteins, organelles, and vesicles. The regulation of microtubule dynamics and stability is critical for the proper functioning of these processes, and TUBAP2 is involved in this regulation.

TUBAP2 has been shown to interact with several key players in the regulation of microtubule dynamics and stability, including microtubule-associated proteins (MAPs). MAPs are a family of proteins that are involved in the regulation of microtubule dynamics and stability, and they play a crucial role in the proper functioning of microtubules. TUBAP2 has been shown to interact with several MAPs, including destination (13), which is involved in the proper delivery of organelles to the cytoplasm.

Another potential drug target of TUBAP2 is its role in the regulation of cell division. The regulation of cell division is critical for the growth and development of cells, and TUBAP2 is involved in this regulation. TUBAP2 has been shown to interact with several key players in the regulation of cell division, including the protein kinesin.

Potential Biomarkers

TUBAP2 has also been identified as a potential biomarker for various diseases due to its unique structure and its involvement in various cellular processes. One of the primary biomarkers for TUBAP2 is its expression level, which can be affected by various factors, including cancer. The expression level of TUBAP2 has been shown to be affected by several factors, including cancer (20), making it a potential biomarker for cancer.

Another potential biomarker for TUBAP2 is its role in the regulation of microtubule dynamics and stability. Microtubule dynamics and stability are critical for the proper functioning of microtubules, and TUBAP2 is involved in this regulation (22).

Protein Name: Tubulin Alpha Pseudogene 2

The "TUBAP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TUBAP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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