TWIST2: A Drug Target / Disease Biomarker (G117581)

Target Name: TWIST2

NCBI ID: G117581

TWIST2

TWIST2: A Drug Target / Disease Biomarker

TWIST2, also known as Twist2, is a protein that is expressed in many different tissues throughout the body. It is a key regulator of cell division and has been implicated in a number of diseases, including cancer. In recent years, researchers have been interested in studying TWIST2 as a potential drug target or biomarker because of its unique biology and the potential it holds for treating a variety of diseases.

The story of TWIST2 began in the 1980s when researchers identified a protein called Twist, which was expressed in many different tissues throughout the body. They found that Twist was involved in the regulation of cell division and that it played a key role in the development of cancer. This discovery led to a further investigation of the Twist family of proteins, which were shown to be involved in a wide range of cellular processes, including cell division, migration, and invasion.

Since then, researchers have made significant progress in understanding the biology of Twist2. They have shown that Twist2 is involved in the regulation of cell growth and that it plays a key role in the development of cancer. They have also found that Twist2 is expressed in many different tissues and that it is involved in the development of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key features of Twist2 is its ability to regulate cell division in a controlled manner. This is important because cells are the foundation of all life, and they are responsible for the growth, repair, and maintenance of the body. If cells are able to divide properly, they are able to replace damaged or diseased cells and help the body to recover from illness. However, if cells divide out of control, they can become cancerous and can cause a variety of diseases.

TWIST2 is thought to regulate cell division by controlling the activity of a protein called cyclin D1. Cyclin D1 is a protein that is involved in the regulation of cell division and is expressed in many different tissues. It is able to interact with Twist2 and prevent it from binding to a protein called p21, which is a key regulator of cell division. This interaction between Twist2 and p21 is important because it allows Twist2 to regulate cell division in a controlled manner.

In addition to its role in cell division, TWIST2 is also involved in the regulation of cell migration and invasion. These processes are important for the development and progression of many diseases, including cancer. TWIST2 is thought to be involved in the regulation of cell migration and invasion by controlling the activity of a protein called vimentin. Vimentin is a protein that is involved in the formation of blood vessels and is expressed in many different tissues. It is thought to interact with Twist2 and regulate the activity of a protein called snail, which is involved in cell migration and invasion.

TWIST2 is also involved in the regulation of many other cellular processes, including the production of proteins, the regulation of inflammation, and the regulation of the immune system. These processes are important for the health and function of the body and are implicated in a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

In conclusion, TWIST2 is a protein that is expressed in many different tissues throughout the body and is involved in a wide range of cellular processes. Its unique biology and the potential it holds for treating a variety of diseases make it an attractive target for research and development. Further studies are needed to fully understand the biology of TWIST2 and to determine its potential as a drug or biomarker.

Protein Name: Twist Family BHLH Transcription Factor 2

Functions: Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (By similarity). Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors

The "TWIST2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TWIST2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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