TWIST: A Potential Drug Target for Cancer (P26050)

Target Name: TWIST

NCBI ID: P26050

TWIST

Other Name(s): TWIST

TWIST: A Potential Drug Target for Cancer

TWIST (Tumor-associated extracellular matrix protein with a unique structure) is a non-specified subtype of extracellular matrix protein (EMP) that has been identified as a potential drug target in cancer. TWIST is a transmembrane protein that is expressed in a variety of tissues, including epithelial, mesenchymal, and neural tissues. It is characterized by a unique structure that consists of a long amino acid sequence that is involved in the formation of a hydrophobic region on the surface of the protein.

The discovery of TWIST as a potential drug target comes from a study by the laboratory of Dr. Yasmina Boudjemaa at the University of Montreal. The study, published in the journal PLoS, found that TWIST was overexpressed in a variety of cancer types, including breast, ovarian, and colorectal cancers. The researchers also found that TWIST was involved in the development of cancer stem cells, which are cells that have the ability to generate new cancerous tumors.

In addition to its potential as a drug target, TWIST has also been identified as a biomarker for cancer. The researchers found that TWIST was overexpressed in a variety of cancer types, including breast, ovarian, and colorectal cancers. They also found that TWIST was able to be used as a marker for the evaluation of cancer stem cells.

The hydrophobic region of TWIST is thought to be the key to its unique structure and its involvement in cancer. The researchers found that the hydrophobic region was able to interact with a variety of different substances, including drugs that are currently being used to treat cancer. This suggests that TWIST could be an effective drug target for cancer.

In conclusion, TWIST is a non-specified subtype of extracellular matrix protein that has been identified as a potential drug target for cancer. Its unique structure, as well as its involvement in the development of cancer stem cells, make TWIST an attractive target for researchers to investigate further. Further studies are needed to determine if TWIST can be used as a reliable biomarker for cancer and to identify potential drugs that can effectively target it.

Protein Name: TWIST (nonspecified Subtype)

The "TWIST Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TWIST comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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