FBP2: A Potential Drug Target and Biomarker for Muscle Disease

Target Name: FBP2

NCBI ID: G8789

FBP2

FBP2: A Potential Drug Target and Biomarker for Muscle Disease

Introduction

FBP2 (muscle glycogen phosphorylase 2) is a protein that is expressed in muscle tissue and is involved in the breakdown of muscle glycogen, which is the body's primary source of stored glucose. Muscle glycogen phosphorylase 2 (FBP2) is A protein expressed in muscle tissue that is involved in the breakdown of muscle glycogen, the source of glucose, the body's primary energy storage form. Muscle glycogen phosphorylase 2 (FBP2) is a protein expressed in muscle cells and involved in the breakdown of muscle glycogen. Muscle glycogen is the source of the body's primary energy storage form, glucose. Phosphorylase is a protein that usually catalyzes chemical reactions.

Muscle disease is a common disorder that affects the physiological function of muscles. These conditions include muscle wasting, muscle weakness, muscle pain, and diabetes. In recent years, researchers have discovered that muscle diseases are related to abnormal expression of FBP2 protein in muscle cells.

Function of FBP2 protein

The FBP2 protein is a kinase involved in multiple metabolic pathways. It plays important roles in muscle cells, including glucose metabolism, fatty acid metabolism, and cell signaling.

The FBP2 protein catalyzes the conversion of glucose-6-phosphate to glucose-6-phosphate, a key step in muscle glycogenolysis. In addition, the FBP2 protein inhibits the entry of calcium ions into muscle cells, thereby reducing the force of muscle contraction.

The role of FBP2 protein in muscle disease

Muscle disease is a common disorder that affects the physiological function of muscles. These conditions include muscle wasting, muscle weakness, muscle pain, and diabetes. In recent years, researchers have discovered that muscle diseases are related to abnormal expression of FBP2 protein in muscle cells.

For example, studies have shown that the activity of the FBP2 protein in muscle cells is significantly elevated in patients with muscle diseases. Additionally, the researchers found that FBP2 protein expression levels were positively correlated with muscle strength and muscle mass in patients with muscle diseases.

Therapeutic effects of FBP2 protein

The role of the FBP2 protein in the treatment of muscle diseases is under intense investigation. For example, researchers are exploring the use of FBP2 protein inhibitors to treat muscle diseases. These inhibitors inhibit the activity of the FBP2 protein, thereby reducing symptoms in patients with muscle diseases.

In addition, researchers are exploring the use of FBP2 protein modulators to treat muscle diseases. These modulators increase the activity of the FBP2 protein, thereby promoting muscle recovery in patients with muscle diseases.

Conclusion

The FBP2 protein has important potential in the treatment of muscle diseases. By inhibiting the activity of the FBP2 protein, muscle diseases, including muscle atrophy, muscle weakness, muscle pain, and diabetes, can be treated. In addition, the FBP2 protein can also serve as a biomarker for muscle diseases, helping doctors in early diagnosis and treatment.

Protein Name: Fructose-bisphosphatase 2

Functions: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate

The "FBP2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FBP2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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