Targeting VPS13C-DT: Methods and Potential (G101928907)

Target Name: VPS13C-DT

NCBI ID: G101928907

VPS13C-DT

Other Name(s): VPS13C divergent transcript

Targeting VPS13C-DT: Methods and Potential

VPS13C-DT, also known as VPS13C-Transcript, is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and developmental disorders. The VPS13C gene is located on chromosome 16 and encodes for the protein VPS13C, which is a key regulator of microtubules, a structure that helps keep cells in a dividing state. Mutations in the VPS13C gene have been linked to a range of disorders, including some forms of cancer, and scientists are increasingly interested in using these mutations as targets for new treatments.

Targeting VPS13C-DT

One approach to targeting VPS13C-DT is to use small molecules, such as drugs, to disrupt the activity of the protein VPS13C. This can be done by binding to a specific epitope (a region of the protein that is important for its function) on the VPS13C protein. Once bound, the small molecule can alter the activity of the protein in a targeted way, such as by inhibiting its ability to form microtubules. This can lead to a disruption of the cell's ability to divide and a range of cellular changes, including the potential for cancer growth and the development of neurodegenerative diseases.

Another approach to targeting VPS13C-DT is to use antibodies, which are proteins that are designed to recognize and bind to specific epitopes on the VPS13C protein. These antibodies can be used to block the activity of the protein in a targeted way, such as by blocking its ability to form microtubules. This can also lead to a disruption of the cell's ability to divide and a range of cellular changes, including the potential for cancer growth and the development of neurodegenerative diseases.

In addition to small molecules and antibodies, researchers are also exploring other approaches to targeting VPS13C-DT, such as using genetic modification to introduce mutations into the VPS13C gene. These mutations, when introduced into the VPS13C protein, can alter its activity and disrupt its regulation of microtubules.

Mechanisms of Action

The VPS13C protein plays a key role in regulating microtubules, which are dynamic structures that help keep cells in a dividing state. Microtubules are made up of a protein called tau, which is involved in the formation of the microtubules. The VPS13C protein helps to regulate the amount of tau protein that forms in the microtubules.

Mutations in the VPS13C gene have been linked to a range of disorders, including some forms of cancer. These mutations can alter the activity of the VPS13C protein and disrupt its regulation of microtubules. This can lead to a range of cellular changes, including the potential for cancer growth and the development of neurodegenerative diseases.

In addition to altering the activity of the VPS13C protein, mutations in the VPS13C gene can also affect the structure and stability of the microtubules. These mutations can lead to changes in the way that the microtubules interact with each other and with other cellular structures, which can have a significant impact on the cellular functions of the cell.

Targeting VPS13C-DT

The potential of VPS13C-DT as a drug target or biomarker is based on its role in regulating microtubules and its association with a range of disorders, including cancer and neurodegenerative diseases. By using small molecules or antibodies to disrupt the activity of the VPS13C protein, researchers are able to alter its activity and disrupt its regulation of microtubules. This can lead to a range of cellular changes, including the potential for cancer growth and the development of neurodegenerative diseases.

In addition to using small molecules or antibodies, researchers are also exploring the use of genetic modification to introduce mutations into the VPS13C gene. These mutations, when introduced into the VPS13C protein, can alter its activity and disrupt its regulation of microtubules. This can provide a more targeted and effective way

Protein Name: VPS13C Divergent Transcript

The "VPS13C-DT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about VPS13C-DT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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