Target Name: ZNF396
NCBI ID: G252884
Review Report on ZNF396 Target / Biomarker Content of Review Report on ZNF396 Target / Biomarker
ZNF396
Other Name(s): Zinc finger protein 396 | ZSCAN14 | ZN396_HUMAN | FLJ31213 | zinc finger protein 396 | ZNF396 variant 3 | Zinc finger protein 396, transcript variant 3 | Zinc finger protein 396 (isoform 2) | zinc finger and SCAN domain-containing protein 14 | Zinc finger and SCAN domain-containing protein 14

ZNF396: A Potential Drug Target and Biomarker

Zinc finger proteins (ZFPs) are a family of transmembrane proteins that play a crucial role in various cellular processes. ZNF396, a specific ZFP, has been identified as a potential drug target and biomarker for various diseases. In this article, we will discuss the structure, function, and potential therapeutic applications of ZNF396.

Structure and Function

ZNF396 is a 21-kDa protein that contains a unique N-terminal zinc finger domain, a N-terminal region, and a C-terminal region that includes a Z-尾 hairpin and a C-terminal domain with a characteristic conserved Structure. The N-terminal region of ZNF396 contains a short amino acid sequence that includes a glutamic acid, which is often associated with zinc finger proteins. The C-terminal region of ZNF396 contains a long amino acid sequence that includes a Z-尾 hairpin and a C-terminal domain with a characteristic conservative structure.

Functional Studies

ZNF396 has been shown to play a crucial role in various cellular processes. Studies have shown that ZNF396 is involved in cell adhesion, migration, and invasion. For instance, ZNF396 has been shown to be involved in the regulation of cell adhesion and migration, including the regulation of tight junction formation and the regulation of cell migration. ZNF396 has also been shown to be involved in the regulation of cell signaling pathways, including the regulation of the PI3K/Akt signaling pathway.

Potential Therapeutic Applications

The therapeutic potential applications of ZNF396 are vast and range from cancer to neurodegenerative diseases. ZNF396 has been shown to be involved in the regulation of various cellular processes, including cell adhesion, migration, and signaling pathways. As such, ZNF396 has the potential to be developed into a drug target for various diseases.

In the context of cancer, ZNF396 has been shown to be involved in the regulation of cell signaling pathways, including the regulation of the PI3K/Akt signaling pathway. This pathway is involved in various cellular processes, including cell growth, survival, and angiogenesis. Therefore, ZNF396 has the potential to be developed into a drug target for cancer, particularly for diseases that are characterized by the over-expression of this pathway, such as breast cancer, lung cancer, and colon cancer.

In the context of neurodegenerative diseases, ZNF396 has been shown to be involved in the regulation of cell signaling pathways, including the regulation of the PDGF/MAPK signaling pathway. This pathway is involved in various cellular processes, including neurotransmitter signaling, learning, and memory . Therefore, ZNF396 has the potential to be developed into a drug target for neurodegenerative diseases, particularly for diseases that are characterized by the over-expression of this pathway, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease.

Conclusion

In conclusion, ZNF396 is a unique and highly conserved protein that has been shown to play a crucial role in various cellular processes. The potential therapeutic applications of ZNF396 are vast and range from cancer to neurodegenerative diseases. Therefore, ZNF396 has the potential to be developed into a drug target for various diseases. Further research is needed to fully understand the function and potential therapeutic applications of ZNF396, as well as to develop safe and effective drugs that target this protein.

Protein Name: Zinc Finger Protein 396

Functions: Isoform 1 and isoform 2 act as DNA-dependent transcriptional repressors

The "ZNF396 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF396 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ZNF397 | ZNF398 | ZNF402P | ZNF404 | ZNF407 | ZNF407-AS1 | ZNF408 | ZNF41 | ZNF410 | ZNF414 | ZNF415 | ZNF416 | ZNF417 | ZNF418 | ZNF419 | ZNF420 | ZNF423 | ZNF425 | ZNF426 | ZNF428 | ZNF429 | ZNF43 | ZNF430 | ZNF431 | ZNF432 | ZNF433 | ZNF433-AS1 | ZNF436 | ZNF436-AS1 | ZNF438 | ZNF439 | ZNF44 | ZNF440 | ZNF441 | ZNF442 | ZNF443 | ZNF444 | ZNF445 | ZNF446 | ZNF449 | ZNF45 | ZNF451 | ZNF454 | ZNF460 | ZNF461 | ZNF462 | ZNF467 | ZNF468 | ZNF469 | ZNF470 | ZNF471 | ZNF473 | ZNF473CR | ZNF479 | ZNF48 | ZNF480 | ZNF483 | ZNF484 | ZNF485 | ZNF486 | ZNF487 | ZNF488 | ZNF490 | ZNF491 | ZNF492 | ZNF493 | ZNF496 | ZNF497 | ZNF497-AS1 | ZNF500 | ZNF501 | ZNF502 | ZNF503 | ZNF503-AS1 | ZNF503-AS2 | ZNF506 | ZNF507 | ZNF510 | ZNF511 | ZNF512 | ZNF512B | ZNF513 | ZNF514 | ZNF516 | ZNF516-DT | ZNF517 | ZNF518A | ZNF518B | ZNF519 | ZNF519P3 | ZNF521 | ZNF524 | ZNF525 | ZNF526 | ZNF527 | ZNF528 | ZNF528-AS1 | ZNF529 | ZNF529-AS1 | ZNF530