ZNF385D-AS1: A Potential Drug Target and Biomarker (G100874216)

ZNF385D-AS1: A Potential Drug Target and Biomarker

Zinc finger proteins (ZFPs) are a family of transmembrane proteins that play a crucial role in gene regulation and are involved in various cellular processes. One of the ZFPs, ZNF385D-AS1, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. In this article, we will explore the biology of ZNF385D-AS1 and its potential as a drug target.

Structure and Function

ZNF385D-AS1 is a 21 kDa protein that is expressed in various tissues, including brain, heart, and muscle. It is a member of the ZNF family, which includes ZNF2, ZNF3, ZNF4, ZNF5, and ZNF6. ZNF385D-AS1 has a unique N-terminus that contains a ZNF-specific domain, a transmembrane segment, and a C-terminus that is similar to other ZFPs.

The ZNF-specific domain is a unique feature of ZNF385D-AS1 that is found in all ZFPs. It is a conserved region that is involved in the regulation of gene expression and cell signaling. The transmembrane segment is responsible for the protein's localization and stability, and the C-terminus is the region that interacts with other proteins, including its partner protein, ZNF217.

Functional Analysis

ZNF385D-AS1 has been shown to play a role in various cellular processes, including cell signaling, gene regulation, and stress response. One of the most significant functions of ZNF385D-AS1 is its role in the regulation of neuronal excitability. ZNF385D-AS1 has been shown to interact with various neurotransmitter receptors, including dopamine, nitric oxide, and GABA.

In addition to its role in neurotransmission, ZNF385D-AS1 has also been shown to play a role in stress response. When cells are exposed to stress, ZNF385D-AS1 is activated and plays a role in the regulation of cellular stress responses, including the expression of genes involved in stress response.

Drug Target Potential

The potential drug target for ZNF385D-AS1 is its unique N-terminus, which contains a ZNF-specific domain. This domain is involved in the regulation of gene expression and cell signaling, making it an attractive target for small molecules. In addition, ZNF385D-AS1 is also a good candidate for a drug target because of its unique structure and the involvement of various cellular processes.

Biomarker Potential

ZNF385D-AS1 has also been shown to be a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. The unique structure of ZNF385D-AS1 makes it a potential biomarker for these diseases, as it is likely to be expressed at different levels in different tissues and cells.

Conclusion

In conclusion, ZNF385D-AS1 is a unique protein that has been shown to play a role in various cellular processes, including cell signaling, gene regulation, and stress response. Its unique N-terminus, which contains a ZNF-specific domain, makes it a potential drug target and biomarker for various diseases. Further research is needed to fully understand the biology of ZNF385D-AS1 and its potential as a drug

Protein Name: ZNF385D Antisense RNA 1

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More Common Targets

ZNF385D-AS2 | ZNF391 | ZNF394 | ZNF395 | ZNF396 | ZNF397 | ZNF398 | ZNF402P | ZNF404 | ZNF407 | ZNF407-AS1 | ZNF408 | ZNF41 | ZNF410 | ZNF414 | ZNF415 | ZNF416 | ZNF417 | ZNF418 | ZNF419 | ZNF420 | ZNF423 | ZNF425 | ZNF426 | ZNF428 | ZNF429 | ZNF43 | ZNF430 | ZNF431 | ZNF432 | ZNF433 | ZNF433-AS1 | ZNF436 | ZNF436-AS1 | ZNF438 | ZNF439 | ZNF44 | ZNF440 | ZNF441 | ZNF442 | ZNF443 | ZNF444 | ZNF445 | ZNF446 | ZNF449 | ZNF45 | ZNF451 | ZNF454 | ZNF460 | ZNF461 | ZNF462 | ZNF467 | ZNF468 | ZNF469 | ZNF470 | ZNF471 | ZNF473 | ZNF473CR | ZNF479 | ZNF48 | ZNF480 | ZNF483 | ZNF484 | ZNF485 | ZNF486 | ZNF487 | ZNF488 | ZNF490 | ZNF491 | ZNF492 | ZNF493 | ZNF496 | ZNF497 | ZNF497-AS1 | ZNF500 | ZNF501 | ZNF502 | ZNF503 | ZNF503-AS1 | ZNF503-AS2 | ZNF506 | ZNF507 | ZNF510 | ZNF511 | ZNF512 | ZNF512B | ZNF513 | ZNF514 | ZNF516 | ZNF516-DT | ZNF517 | ZNF518A | ZNF518B | ZNF519 | ZNF519P3 | ZNF521 | ZNF524 | ZNF525 | ZNF526 | ZNF527