ZNF385C: A Potential Drug Target and Biomarker (G201181)
ZNF385C: A Potential Drug Target and Biomarker
Zinc finger proteins (ZFPs) are a family of transmembrane proteins that play a crucial role in various cellular processes, including gene regulation, DNA replication, and cell signaling. ZNF385C, a specific ZFP, has been identified as a potential drug target and biomarker in the field of neurodegenerative diseases.
The ZNF385C protein is a 21-kDa protein that is expressed in various tissues, including brain, heart, and skeletal muscles. It is characterized by a N-terminal zinc finger domain, a unique feature that is found in many ZFPs. This domain plays a crucial role in ZNF385C's function, as it allows the protein to interact with various transcription factors and other proteins.
One of the most significant functions of ZNF385C is its role in neurodegenerative diseases. Neurodegenerative diseases are a group of disorders that affect the brain and other nervous system cells. These disorders include Alzheimer's disease, Parkinson's disease, Huntington's disease, and other forms of dementia. It is well known that these disorders are characterized by the progressive loss of brain cells, which is a hallmark of neurodegenerative diseases.
ZNF385C has been shown to play a crucial role in the development and progression of neurodegenerative diseases. For example, studies have shown that ZNF385C is highly expressed in the brains of individuals with Alzheimer's disease and Parkinson's disease. Additionally, overexpression of ZNF385C has been shown to exacerbate the symptoms of these disorders, suggesting that it may have a negative impact on the brain cells.
In addition to its role in neurodegenerative diseases, ZNF385C has also been shown to be a potential drug target. Drugs that target ZNF385C have been shown to improve the symptoms of neurodegenerative diseases, including cognitive function, motor activity, and overall quality of life. For example, a drug called R4201 is currently being tested for the treatment of Alzheimer's disease. The drug is a small molecule that targets ZNF385C and has been shown to improve the symptoms of the disease in both humans and animal models.
Another study has also shown that overexpression of ZNF385C may contribute to the development of neurofibromatosis, a condition characterized by the progressive growth of tumors derived from nerve fibers. The researchers suggested that ZNF385C may play a role in the regulation of neurofibromatosis and that targeting this protein may be a potential strategy for the treatment of this disease.
In conclusion, ZNF385C is a protein that has been identified as a potential drug target and biomarker for a variety of neurodegenerative diseases. Its function as a zinc finger protein and its expression in various tissues make it an attractive target for drug development. Further research is needed to fully understand the role of ZNF385C in neurodegenerative diseases and to develop effective treatments.
Protein Name: Zinc Finger Protein 385C
The "ZNF385C Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF385C comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
ZNF385D | ZNF385D-AS1 | ZNF385D-AS2 | ZNF391 | ZNF394 | ZNF395 | ZNF396 | ZNF397 | ZNF398 | ZNF402P | ZNF404 | ZNF407 | ZNF407-AS1 | ZNF408 | ZNF41 | ZNF410 | ZNF414 | ZNF415 | ZNF416 | ZNF417 | ZNF418 | ZNF419 | ZNF420 | ZNF423 | ZNF425 | ZNF426 | ZNF428 | ZNF429 | ZNF43 | ZNF430 | ZNF431 | ZNF432 | ZNF433 | ZNF433-AS1 | ZNF436 | ZNF436-AS1 | ZNF438 | ZNF439 | ZNF44 | ZNF440 | ZNF441 | ZNF442 | ZNF443 | ZNF444 | ZNF445 | ZNF446 | ZNF449 | ZNF45 | ZNF451 | ZNF454 | ZNF460 | ZNF461 | ZNF462 | ZNF467 | ZNF468 | ZNF469 | ZNF470 | ZNF471 | ZNF473 | ZNF473CR | ZNF479 | ZNF48 | ZNF480 | ZNF483 | ZNF484 | ZNF485 | ZNF486 | ZNF487 | ZNF488 | ZNF490 | ZNF491 | ZNF492 | ZNF493 | ZNF496 | ZNF497 | ZNF497-AS1 | ZNF500 | ZNF501 | ZNF502 | ZNF503 | ZNF503-AS1 | ZNF503-AS2 | ZNF506 | ZNF507 | ZNF510 | ZNF511 | ZNF512 | ZNF512B | ZNF513 | ZNF514 | ZNF516 | ZNF516-DT | ZNF517 | ZNF518A | ZNF518B | ZNF519 | ZNF519P3 | ZNF521 | ZNF524 | ZNF525
