Huntington's Disease: A Protein's Role in Its Treatment (G55893)
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Huntington's Disease: A Protein's Role in Its Treatment
Huntington disease is a progressive neurodegenerative disorder that is characterized by the progressive loss of motor neurons. It is caused by a deficiency of dystrophin, a protein that helps keep the brain cells healthy. The Huntingtin gene is a key regulator of dystrophin production and is mutated in most cases of Huntington disease. The Huntingtin gene has four isoforms, two of which are functional and the other two of which are not. ZNF395 is a protein that is expressed in the brain and has been shown to interact with the Huntingtin gene. It is also known as Huntington disease gene regulatory region-binding protein 2 and has been shown to be a potential drug target for the treatment of Huntington disease.
The Huntingtin gene is a highly conserved gene that is located on chromosome 16p. It has four exons, which are the first four amino acids that make up the gene. The first exon codes for the N-terminus of the protein, the second exon codes for the M-terminus, the third exon codes for the L-terminus, and the fourth exon codes for the R-terminus. The N-terminus of the protein contains a nuclear localization signal that is important for the protein's ability to interact with DNA. The M-terminus of the protein contains a series of basic amino acids that are important for protein stability. The L-terminus of the protein contains a series of acidic amino acids that help to maintain the protein's stability and localize to the nucleus. The R-terminus of the protein contains a series of basic amino acids that are important for protein stability.
Huntington disease is a progressive neurodegenerative disorder that is characterized by the progressive loss of motor neurons. It is caused by a deficiency of dystrophin, a protein that helps keep the brain cells healthy. The Huntingtin gene is a key regulator of dystrophin production and is mutated in most cases of Huntington disease. The huntingtin gene has four isoforms, two of which are functional and the other two of which are not. ZNF395 is a protein that is expressed in the brain and has been shown to interact with the huntingtin gene. It is also known as Huntington disease gene regulatory region-binding protein 2 and has been shown to be a potential drug target for the treatment of Huntington disease.
ZNF395 is a protein that is expressed in the brain and has been shown to interact with the huntingtin gene. It is also known as Huntington disease gene regulatory region-binding protein 2 and has been shown to be a potential drug target for the treatment of Huntington disease. ZNF395 is a small protein that contains 115 amino acids. It has a molecular weight of 17 kDa and a pI of 11.95. ZNF395 is expressed in the brain and has been shown to interact with the huntingtin gene in the nucleus. It is also shown to interact with the
Protein Name: Zinc Finger Protein 395
Functions: Plays a role in papillomavirus genes transcription
The "ZNF395 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF395 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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