MTMR2: A Potential Drug Target and Biomarker (G8898)

Target Name: MTMR2

NCBI ID: G8898

MTMR2

MTMR2: A Potential Drug Target and Biomarker

MTMR2 (phosphatidylinositol-3,5-bisphosphate 3-phosphatase) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key enzyme in the intracellular signaling pathway known as the PI3K/Akt pathway, which plays a crucial role in regulating various cellular processes, including cell growth, differentiation, and survival.

MTMR2 has been identified as a potential drug target or biomarker due to its involvement in this signaling pathway. The PI3K/Akt pathway is a highly validated target for drug development, with many approved drugs currently in use that target this pathway. MTMR2 is also a good candidate for a biomarker, as its expression is often elevated in diseases associated with inflammation, such as cancer and autoimmune disorders.

In addition to its potential drug-targeting properties, MTMR2 has also been shown to have a number of potential therapeutic applications. For example, MTMR2 has been shown to be involved in the regulation of neuronal excitability, which is important for normal brain function. It has also been shown to play a role in the regulation of pain perception, which is a key aspect of human quality of life.

MTMR2 is also a potential target for diagnostic purposes, as its expression is often elevated in certain diseases, such as cancer and neurodegenerative disorders. This makes it a promising candidate for diagnostic biomarkers.

In conclusion, MTMR2 is a protein that has a number of potential therapeutic and diagnostic applications. Its involvement in the PI3K/Akt pathway makes it a promising candidate for drug targeting, and its expression in various diseases makes it a promising candidate for diagnostic biomarkers. Further research is needed to fully understand the role of MTMR2 in cellular signaling and its potential as a drug or biomarker.

Protein Name: Myotubularin Related Protein 2

Functions: Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate (PubMed:11733541, PubMed:12668758, PubMed:21372139, PubMed:14690594). Binds phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate (By similarity). Stabilizes SBF2/MTMR13 at the membranes (By similarity). Specifically in peripheral nerves, stabilizes SBF2/MTMR13 protein (By similarity)

The "MTMR2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MTMR2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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