Target Name: MUC1
NCBI ID: G4582
Review Report on MUC1 Target / Biomarker Content of Review Report on MUC1 Target / Biomarker
MUC1
Other Name(s): Mucin-1 | MCKD1 | Mucin 1, cell surface associated, transcript variant 2 | MCD | MUC1 variant 1 | Mucin 1, cell surface associated, transcript variant 1 | OTTHUMP00000033790 | Mucin-1 (isoform 10) | peanut-reactive urinary mucin | Mucin-1 (isoform 2) | ADMCKD1 | Medullary cystic kidney disease, autosomal dominant | carcinoma-associated mucin | Tumor associated epithelial mucin | ADMCKD | MUC1-beta | CD227 antigen | DF3 antigen | OTTHUMP00000033795 | Mucin | Cancer antigen 15-3 | Mucin-1 (isoform 1) | PUM | Episialin | CA 15-3 | polymorphic epithelial mucin | KL-6 | Tumor-associated epithelial membrane antigen | medullary cystic kidney disease 1 (autosomal dominant) | Mucin-1 (isoform 5) | Mucin-1 (alpha)_(HUMAN) | MCKD | H23 antigen | Polymorphic epithelial mucin | PEMT | EMA | Mucin-1 (beta)_HUMAN | MUC-1/X | episialin | Mucin-1 (beta)_(HUMAN) | tumor-associated epithelial membrane antigen | mucin 1, cell surface associated | H23AG | Tumor-associated mucin | Krebs von den Lungen-6 | Mucin-1 subunit beta | cancer antigen 15-3 | MUC1 isoform T12 | MUC1_HUMAN | Mucin 1, cell surface associated, transcript variant 5 | MUC1 isoform T13 | MAM6 | mucin 1, transmembrane | ADTKD2 | Mucin 1, transmembrane | Peanut-reactive urinary mucin | Mucin-1 subunit alpha | MUC1-alpha | Breast carcinoma-associated antigen DF3 | MUC1 variant 10 | MUC1/ZD | krebs von den Lungen-6 | MUC1 variant 2 | MUC-1/SEC | MUC1 isoform T10 | MUC1 variant 5 | CD227 | MUC1-NT | tumor associated epithelial mucin | MUC1-CT | MUC1 isoform T11 | Ca15-3 | MUC1/SV3 | OTTHUMP00000033787 | MUC-1 | Mucin 1, cell surface associated, transcript variant 10 | Mucin-1 (alpha)_HUMAN | Carcinoma-associated mucin | breast carcinoma-associated antigen DF3 | PEM

Understanding MUC1: Potential Drug Target and Biomarker

MUC1 (Mucin-1) is a gene that encodes a protein known as MUC1. MUC1 is a type of glycoprotein that is expressed in many different cell types in the body. It is a major component of the extracellular matrix (ECM), which is a complex mixture of proteins, carbohydrates, and other molecules that is present in all cells and tissues of the body. MUC1 is one of the most widely expressed proteins in the human body, and it is expressed in high levels in many different tissues, including the skin, the lungs, the heart, and the brain.

MUC1 has been identified as a potential drug target for a variety of diseases. Its role in many different biological processes makes it an attractive target for researchers to study and potentially exploit for the development of new treatments. Some studies have suggested that MUC1 may be involved in the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key challenges in studying MUC1 and its potential as a drug target is its complex structure. MUC1 is a large protein that contains many different domains, including an extracellular domain, a transmembrane domain, and an intracellular domain. The functions of these different domains are not yet fully understood, and researchers are still working to determine exactly how MUC1 functions in the body.

In addition to its potential as a drug target, MUC1 is also a biomarker for a variety of diseases. Its high expression levels in many different tissues make it a useful indicator of the presence of certain diseases, such as cancer. This makes MUC1 an attractive target for researchers to study as a potential diagnostic tool.

Another potential application of MUC1 as a drug target is its role in the development of certain types of cancer. Many studies have suggested that MUC1 may be involved in the development and progression of breast, ovarian, and prostate cancers. Researchers are working to determine exactly how MUC1 contributes to the development of these cancers and to identify potential drug targets.

In addition to its potential as a cancer drug target, MUC1 is also being studied for its potential as a neurodegenerative disease drug target. MUC1 is expressed in high levels in the brain and is involved in the formation of the ECM, which is thought to play a role in the development and progression of neurodegenerative diseases. Researchers are working to determine exactly how MUC1 contributes to the development and progression of these diseases and to identify potential drug targets.

Overall, MUC1 is a complex and highly expressed protein that is involved in many different biological processes in the body. Its potential as a drug target and biomarker make it an attractive target for researchers to study and may lead to new treatments for a variety of diseases . Further research is needed to fully understand the functions of MUC1 and its potential as a drug and biomarker.

Protein Name: Mucin 1, Cell Surface Associated

Functions: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack

The "MUC1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MUC1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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