MTRFR: A Potential Drug Target for Various Diseases (G91574)

Target Name: MTRFR

NCBI ID: G91574

MTRFR

MTRFR: A Potential Drug Target for Various Diseases

MTRFR (Chromosome 12 open reading frame 65) is a gene that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and psychiatric disorders. MTRFR is a gene that encodes a protein known as MTRF, which plays a critical role in the regulation of cellular processes that are involved in the development and progression of these diseases.

The MTRFR gene was first identified in the late 1990s using transcriptome analysis of human chromosome 12. The open reading frame (ORF) of the gene is 65 amino acids long and is located on the short arm of chromosome 12. MTRF is a protein that is expressed in various tissues and cells of the body, including brain, muscle, and blood cells.

Initial studies have suggested that MTRF may be involved in the regulation of several cellular processes that are involved in the development and progression of diseases, including cancer, neurodegenerative diseases, and psychiatric disorders. For example, MTRF has been shown to be involved in the regulation of cell division, which is a critical process that is involved in the development and progression of cancer. In addition, MTRF has been shown to be involved in the regulation of neural development and differentiation, which is critical for the development and progression of neurodegenerative diseases.

In addition to its potential role in the regulation of cellular processes, MTRF has also been shown to be involved in the regulation of cellular signaling pathways. For example, MTRF has been shown to be involved in the regulation of the JAK/STAT signaling pathway, which is involved in the regulation of cellular signaling pathways that are involved in the development and progression of many diseases, including cancer, neurodegenerative diseases, and psychiatric disorders.

Due to its involvement in several cellular processes that are involved in the development and progression of diseases, MTRF has been identified as a potential drug target or biomarker for a variety of diseases. For example, MTRF has been shown to be involved in the regulation of cell division, which is a critical process that is involved in the development and progression of cancer. In addition, MTRF has been shown to be involved in the regulation of neural development and differentiation, which is critical for the development and progression of neurodegenerative diseases.

In addition to its potential role in the regulation of cellular processes, MTRF has also been shown to be involved in the regulation of cellular signaling pathways. For example, MTRF has been shown to be involved in the regulation of the JAK/STAT signaling pathway, which is involved in the regulation of cellular signaling pathways that are involved in the development and progression of many diseases, including cancer, neurodegenerative diseases, and psychiatric disorders.

Recent studies have also suggested that MTRF may be involved in the regulation of other cellular processes that are involved in the development and progression of diseases. For example, MTRF has been shown to be involved in the regulation of cell adhesion, which is critical for the development and progression of many diseases, including cancer. In addition, MTRF has been shown to be involved in the regulation of cell migration, which is critical for the development and progression of many diseases, including cancer.

In conclusion, MTRFR (Chromosome 12 open reading frame 65) is a gene that has been identified as a potential drug target or biomarker for various diseases. Its involvement in the regulation of cellular processes that are involved in the development and progression of diseases makes it an attractive target for researchers to investigate further. Further studies are needed to fully understand the role of MTRF in the development and progression of diseases.

Protein Name: Mitochondrial Translation Release Factor In Rescue

Functions: Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation (PubMed:33243891). As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis factors to these quality control intermediates suggests additional roles for MTRES1 and MTRF during mitoribosome rescue (PubMed:33243891)

The "MTRFR Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MTRFR comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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