MTPN: A Potential Drug Target Or Biomarker (G136319)

Target Name: MTPN

NCBI ID: G136319

MTPN

MTPN: A Potential Drug Target Or Biomarker

Mesothelin-related peptide (MTPN) is a protein that is expressed in various tissues of the body, including the skin, heart, and nervous system. It is a transmembrane glycoprotein that consists of four transmembrane 伪-helical domains. MTPN has a variety of biological functions, including participating in cell signal transduction, cell adhesion, cell migration and tumorigenesis. In recent years, researchers have conducted in-depth studies on MTPN and found that it plays an important role in many diseases. In addition, MTPN has also been found to be a potential drug target or biomarker. This article will introduce the structure, function, mechanism of action of MTPN and its potential value in drug research and clinical application.

Biological functions of MTPN

MTPN is a transmembrane protein expressed in a variety of cells and tissues. It plays an important role in cell signaling, adhesion, migration, and tumorigenesis. The main biological functions of MTPN include:

1. Participate in cell signal transduction

MTPN plays a role in many signal transduction pathways, including GFR, EGFR, NF-kappa-B and Hedgehog signaling pathways. MTPN can regulate these signal transduction pathways by interacting with other proteins, such as FAK, PDGFR and MAPK.

2. Participate in cell adhesion

MTPN plays an important role in cell adhesion. Studies have shown that MTPN can interact with proteins such as integrins to increase the combination of cells and matrix, thereby enhancing cell adhesion.

3. Participate in cell migration

MTPN plays an important role in cell migration. Studies have shown that MTPN can regulate multiple steps of cell migration, including intracellular transport, extracellular stiffness, and extracellular matrix response.

4. Participate in tumorigenesis

MTPN also plays an important role in tumorigenesis. Studies have shown that MTPN can promote the invasion and metastasis of tumor cells, and can also regulate the growth and apoptosis of tumor cells.

MTPN鈥檚 mechanism of action

The mechanism of action of MTPN is to regulate cell signal transduction, adhesion, migration and tumorigenesis in various ways. The main mechanisms of action of MTPN include:

1. Regulate cell signal transduction

MTPN can regulate cell signal transduction pathways by interacting with proteins, such as FAK, PDGFR and MAPK. MTPN can increase the phosphorylation level of FAK, thereby enhancing cell adhesion and post-adhesion signal transduction. In addition, MTPN can also increase cell adhesion and migration by regulating the activity of signal transduction pathways such as EGFR and MAPK.

2. Regulate cell adhesion

MTPN plays an important role in cell adhesion. MTPN can interact with proteins such as integrins to increase the combination of cells and matrix, thereby enhancing cell adhesion. In addition, MTPN can also increase cell adhesion by regulating the activity of proteins such as integrins.

3. Regulate cell migration

MTPN plays an important role in cell migration. MTPN can regulate multiple steps of cell migration, including intracellular transport, extracellular stiffness, and extracellular matrix response. MTPN can increase cell migration by regulating the stiffness of the cytoskeleton, extracellular matrix response, and intracellular transport.

4. Regulate tumorigenesis

MTPN also plays an important role in tumorigenesis. MTPN can promote the invasion and metastasis of tumor cells, and can also regulate the growth and apoptosis of tumor cells. MTPN can increase the invasion and metastasis of tumor cells by regulating tumor cell growth factor receptors, intracellular trafficking, and extracellular matrix responses.

Potential value of MTPN in drug research and clinical application

MTPN has important potential value in drug research and clinical application. Since MTPN plays an important role in a variety of diseases, studying MTPN as a drug target or biomarker has good prospects.

First, for MTP

Protein Name: Myotrophin

Functions: Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy

The "MTPN Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MTPN comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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