GADD45GIP1: Potential Drug Target Or Biomarker (G90480)

Target Name: GADD45GIP1

NCBI ID: G90480

GADD45GIP1

GADD45GIP1: Potential Drug Target Or Biomarker

GADD45GIP1 (CKbetaBP2) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the GADD45 family of proteins, which are known for their role in intracellular signaling. GADD45GIP1 has been shown to play a role in a variety of physiological processes, including cell signaling, inflammation, and neurodegeneration. As a result, GADD45GIP1 has potential as a drug target or biomarker.

The GADD45 family of proteins is characterized by the presence of a conserved catalytic domain and a unique N-terminus. This conserved catalytic domain is known as the GADD domain, and it is thought to play a role in the protein's intracellular signaling functions. The N-terminus of GADD45GIP1 is rich in acidic amino acids, which are thought to contribute to the protein's ability to interact with various signaling molecules.

GADD45GIP1 has been shown to play a role in a variety of physiological processes. For example, GADD45GIP1 has been shown to be involved in neurotransmitter signaling, including the regulation of neurotransmitter release and uptake. In addition, GADD45GIP1 has been shown to be involved in inflammation, including the regulation of immune cell function and the production of pro-inflammatory cytokines.

GADD45GIP1 has also been shown to be involved in a variety of cellular processes that are important for maintaining tissue homeostasis. For example, GADD45GIP1 has been shown to play a role in the regulation of cell volume and the maintenance of blood pressure, as well as in the regulation of ion homeostasis and water balance.

GADD45GIP1 has been shown to be involved in a variety of diseases and disorders, including neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. In addition, GADD45GIP1 has been shown to be involved in a variety of metabolic processes, including the regulation of glucose metabolism and lipid metabolism.

GADD45GIP1 is also a good candidate as a biomarker for certain diseases, such as cancer. Its expression has been shown to be elevated in a variety of cancer types, including breast, lung, and colorectal cancer. Additionally, GADD45GIP1 has been shown to be involved in the regulation of cell cycle progression, which is a key aspect of cancer development.

GADD45GIP1 has also been shown to be involved in the regulation of pain perception and neuroinflammation. Its expression has been shown to be elevated in the brains of individuals with chronic pain, and its levels have also been shown to be elevated in the brains of individuals with neuroinflammation.

GADD45GIP1 is also a good candidate as a drug target for treating certain diseases. Its expression has been shown to be elevated in a variety of diseases, including neurodegenerative diseases, neuroinflammation, and certain metabolic disorders. Additionally, GADD45GIP1 has been shown to play a role in the regulation of intracellular signaling pathways, which are often disrupted in these diseases.

In conclusion, GADD45GIP1 is a protein that is expressed in various tissues of the body and has been shown to play a role in a variety of physiological processes. Its conserved catalytic domain and unique N-terminus make it a potential drug target or biomarker. Further research is needed to fully understand the role of GADD45GIP1 in various biological processes and to explore its potential as a drug

Protein Name: GADD45G Interacting Protein 1

Functions: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis

The "GADD45GIP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GADD45GIP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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