Target Name: GANAB
NCBI ID: G23193
Review Report on GANAB Target / Biomarker Content of Review Report on GANAB Target / Biomarker
GANAB
Other Name(s): GANAB variant 2 | Glucosidase II alpha subunit, transcript variant 3 | alpha Glucosidase II alpha subunit | Alpha glucosidase II alpha subunit | alpha-Glucosidase 2 | GANAB_HUMAN | Neutral alpha-glucosidase AB | GLUII | G2AN | Alpha-glucosidase 2 | Neutral alpha-glucosidase AB (isoform 2) | GANAB variant 3 | Neutral alpha-glucosidase AB (isoform 3) | alpha-glucosidase 2 | PKD3 | GIIA | Glucosidase II subunit alpha | KIAA0088 | glucosidase II alpha subunit | Glucosidase II alpha subunit, transcript variant 2 | GluII

GANAB: A Potential Drug Target and Biomarker for Psychiatric Conditions

GANAB (GANAB variant 2) is a protein that is expressed in the brain and has been shown to play a role in various neurological and psychiatric conditions, including depression, anxiety, and schizophrenia. While the exact function of GANAB is not yet fully understood, research has identified several potential drug targets and biomarkers that may be associated with this protein.

One of the primary drug targets for GANAB is its role in synaptic plasticity, which is the ability of the brain to change and adapt over time. GANAB has been shown to play a role in the regulation of synaptic plasticity, which may contribute to its potential as a drug target.

Another potential drug target for GANAB is its role in mood regulation. GANAB has been shown to be involved in the regulation of mood, and changes in GANAB levels have been linked to changes in mood. Therefore, drugs that target GANAB may have potential as antidepressants or antipsychotics.

In addition to its potential as a drug target, GANAB has also been identified as a potential biomarker for various psychiatric conditions. The levels of GANAB have been shown to be abnormal in individuals with depression, anxiety, and schizophrenia, which may suggest that these conditions are associated with changes in GANAB levels. Therefore, GANAB levels may be a potential biomarker for these conditions.

While more research is needed to fully understand the function of GANAB, its potential as a drug target and biomarker make it a promising target for future research. As such, GANAB is likely to continue to be a focus of research in the coming years, with the potential to revolutionize our understanding of various psychiatric and neurological conditions.

Protein Name: Glucosidase II Alpha Subunit

Functions: Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:10929008). Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia (PubMed:27259053)

The "GANAB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GANAB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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