GARIN4: A Potential Drug Target and Biomarker (G149647)

Target Name: GARIN4

NCBI ID: G149647

GARIN4

GARIN4: A Potential Drug Target and Biomarker

GARIN4, a protein family with sequence similarity 71 member A, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. This protein is expressed in various tissues and organs, including the brain, spinal cord, heart, and pancreas, and is involved in various cellular processes that are crucial for their function.

The GARIN4 protein is a key regulator of the microtubule network, which is a complex of filaments that transports proteins and organelles within cells. Microtubules play a critical role in cell division, intracellular transport, and regulation of various cellular processes. GARIN4 is a key regulator of the microtubule network, and its dysfunction has been implicated in various diseases.

GARIN4 has been shown to be involved in various cellular processes that are crucial for maintaining cellular homeostasis. For example, GARIN4 has been shown to regulate the dynamics of mitochondria, which are critical for energy metabolism and cell survival. Additionally, GARIN4 has been shown to regulate the transport of organelles, including the transport of neurotransmitters and other signaling molecules.

GARIN4 has also been shown to be involved in the regulation of the cytoskeleton. The cytoskeleton is a complex of filaments and fibers that provides structural support to cells and helps maintain their shape and stability. GARIN4 is involved in the regulation of the cytoskeleton by controlling the assembly and disassembly of microtubules.

GARIN4 has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. For example, GARIN4 has been shown to be involved in the development and progression of neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. Additionally, GARIN4 has been shown to be involved in the regulation of the blood-brain barrier, which is responsible for controlling the movement of substances into and out of the brain. The dysfunction of the blood-brain barrier has been implicated in various neurological disorders, including Alzheimer's disease.

In addition to its involvement in neurodegenerative diseases, GARIN4 has also been implicated in the regulation of cancer progression. For example, GARIN4 has been shown to be involved in the regulation of cell division and the maintenance of the stem-like properties of cancer cells. Additionally, GARIN4 has been shown to be involved in the regulation of angiogenesis, which is the process by which new blood vessels are formed. The dysfunction of angiogenesis has been implicated in various diseases, including cancer.

GARIN4 has also been shown to be involved in the regulation of various signaling pathways that are involved in cellular processes that are crucial for cell survival. For example, GARIN4 has been shown to be involved in the regulation of theNotch signaling pathway, which is involved in the regulation of stem cells and their differentiation. Additionally, GARIN4 has been shown to be involved in the regulation of the TGF-β signaling pathway, which is involved in the regulation of cell growth and differentiation.

In conclusion, GARIN4 is a protein family with sequence similarity 71 member A that is involved in various cellular processes that are crucial for maintaining cellular homeostasis. The dysfunction of GARIN4 has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Therefore, GARIN4 is a potential drug target and biomarker for these diseases. Further research is needed to fully understand the role of GARIN4 in these diseases and to develop effective therapies that target this protein.

Protein Name: Golgi Associated RAB2 Interactor Family Member 4

Functions: RAB2B effector protein required for the compacted Golgi morphology, probably through interaction with small GTPase RAB2B

The "GARIN4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GARIN4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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